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Recruiting NCT07266675

Post-Acute Phase of Cardiogenic Shock

Observational Cardiogenic Shock

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Cardiogenic Shock. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Taiwan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Post-Acute Phase of Cardiogenic Shock (PACS) Registry

Overview

Epidemiology studies showed that the burden of cardiogenic shock (CS) persistently high, with increasing annual medical expenses and steady prevalence. In-hospital and one-year mortality reduce annually. Hence, there are increasing number of patients who survive to hospital discharge but they will face further challenges in the subacute stage after hospital discharge. However, there are still insufficient studies focusing on this issue. Establishment of a healthcare neatwork to help hospital survivors of CS return society safely is critical.

Detailed description

Multicener, prospective cohort study

Primary outcome measures

  • mortality [Time frame: 1 year]
  • rehospitalization [Time frame: 1 year]
Secondary outcome measures (4)
  • mortality [Time frame: 90-day]
  • rehospitalization [Time frame: 90-day]
  • mortality [Time frame: 180-day]
  • rehospitalization [Time frame: 180-day]

Eligibility criteria

Inclusion criteria

Hospital survivors of cardiogenic shock

Exclusion criteria

  • Age < 18 years。
  • Patient or family refuse follow-up.
  • Patient died within hospital stay.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Taiwan · 1 center
  • MacKay Memorial Hospital — Taipei

Publications

  • Chien SC, Hsu CY, Liu HY, Lin CF, Hung CL, Huang CY, Chien LN. Cardiogenic shock in Taiwan from 2003 to 2017 (CSiT-15 study). Crit Care. 2021 Nov 18;25(1):402. doi: 10.1186/s13054-021-03820-1. PMID 34794502
  • Shah M, Patil S, Patel B, Agarwal M, Davila CD, Garg L, Agrawal S, Kapur NK, Jorde UP. Causes and Predictors of 30-Day Readmission in Patients With Acute Myocardial Infarction and Cardiogenic Shock. Circ Heart Fail. 2018 Apr;11(4):e004310. doi: 10.1161/CIRCHEARTFAILURE.117.004310. PMID 29618581
  • Vallabhajosyula S, Payne SR, Jentzer JC, Sangaralingham LR, Kashani K, Shah ND, Prasad A, Dunlay SM. Use of Post-Acute Care Services and Readmissions After Acute Myocardial Infarction Complicated by Cardiac Arrest and Cardiogenic Shock. Mayo Clin Proc Innov Qual Outcomes. 2021 Feb 8;5(2):320-329. doi: 10.1016/j.mayocpiqo.2020.12.006. eCollection 2021 Apr. PMID 33997631
  • Shah M, Patnaik S, Patel B, Ram P, Garg L, Agarwal M, Agrawal S, Arora S, Patel N, Wald J, Jorde UP. Trends in mechanical circulatory support use and hospital mortality among patients with acute myocardial infarction and non-infarction related cardiogenic shock in the United States. Clin Res Cardiol. 2018 Apr;107(4):287-303. doi: 10.1007/s00392-017-1182-2. Epub 2017 Nov 13. PMID 29134345
  • Shah RU, de Lemos JA, Wang TY, Chen AY, Thomas L, Sutton NR, Fang JC, Scirica BM, Henry TD, Granger CB. Post-Hospital Outcomes of Patients With Acute Myocardial Infarction With Cardiogenic Shock: Findings From the NCDR. J Am Coll Cardiol. 2016 Feb 23;67(7):739-47. doi: 10.1016/j.jacc.2015.11.048. PMID 26892407
  • Aissaoui N, Puymirat E, Simon T, Bonnefoy-Cudraz E, Angoulvant D, Schiele F, Benamer H, Quandalle P, Prunier F, Durand E, Berard L, Blanchard D, Danchin N. Long-term outcome in early survivors of cardiogenic shock at the acute stage of myocardial infarction: a landmark analysis from the French registry of Acute ST-elevation and non-ST-elevation Myocardial Infarction (FAST-MI) Registry. Crit Care. PMID 25246084
  • Chien SC, Wang CA, Liu HY, Lin CF, Huang CY, Chien LN. Comparison of the prognosis among in-hospital survivors of cardiogenic shock based on etiology: AMI and Non-AMI. Ann Intensive Care. 2024 May 12;14(1):74. doi: 10.1186/s13613-024-01305-2. PMID 38735891

Identifiers

NCT: NCT07266675 · 24MMHIS216e

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗