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Not yet recruiting NCT07265063

Pulpotomy With CEM vs Pulpectomy With Ca(OH)2/Iodoform in Primary Molars

No phase Interventional Carious Primary Molars

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Pulpotomy using Calcium-Enriched Mixture (CEM) Cement, Pulpectomy using Calcium Hydroxide/Iodoform Paste (Metapex).
Who it may be relevant to
Registry conditions: Carious Primary Molars. Basic parameters: 6 years — 8 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Clinical and Radiographic Evaluation of Pulpotomy Using Calcium-Enriched Mixture Versus Pulpectomy Using Calcium Hydroxide/Iodoform Paste for the Treatment of Primary Molars With Irreversible Pulpitis: A Randomized Clinical Trial

Overview

Will Calcium-Enriched Mixture (CEM) cement pulpotomy have less postoperative pain and more clinical and radiographic success compared to Calcium Hydroxide/Iodoform (Metapex) pulpectomy when managing second primary molars with irreversible pulpitis?

Interventions

  • Procedure Pulpotomy using Calcium-Enriched Mixture (CEM) Cement
    pulpotomy procedure using (CEM) Cement as pulp dressing material
  • Procedure Pulpectomy using Calcium Hydroxide/Iodoform Paste (Metapex)
    pulpectomy procdure performed using Metapex paste as root canal filling material

Primary outcome measures

  • Postoperative Pain Intensity [Time frame: 1, 3, 6, 9, and 12 months post-treatment]
Secondary outcome measures (2)
  • Evaluation of Clinical Success [Time frame: 1, 3, 6, 9, and 12 months post-treatment]
  • Evaluation of Radiographic Success [Time frame: 6 and 12 months post-treatment]

Eligibility criteria

Inclusion criteria

  • Children:

Aged 6-8 years of both sexes. Cooperative and medically free. Diagnosed with irreversible pulpitis based on clinical and radiographic criteria.

Parents/legal guardians provide written informed consent. Parents able to attend follow-up visits.

Teeth:

Deep carious second primary molars with signs of irreversible pulpitis. No clinical signs of necrosis (abscess, fistula, mobility). No radiographic signs of necrosis (periapical lesion or resorption).

Exclusion criteria

  • Children:

With systemic or mental disorders. Whose parents refuse to give consent. Uncooperative behavior.

Teeth:

Signs of pulpal necrosis (swelling, fistula, pathological mobility). Periapical or furcal radiolucency exceeding half the furcation-apical distance. Non-restorable teeth, root caries, internal/external resorption, or calcified canals.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07265063 · CEMvsCHIP2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗