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Enrolling by invitation NCT07260318

Acute Effects of Cricket Fast Bowling on Bone Turnover and Signaling Markers

No phase Interventional Health Adults

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Exercise.
Who it may be relevant to
Registry conditions: Health Adults. Basic parameters: 18 years — 30 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United Kingdom
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Overview

The goal of this study is to investigate the acute effects of cricket fast bowling on the bone turnover and signaling markers in healthy young males. The main question aims to answer: • Does a single bout acute fast bowling change serum C-terminal telopeptide of type I collagen (CTX-I) and other bone turnover and signaling markers levels? Participants complete both the bowling and control trials, with a minimum washout period of one week between trials. During each trial, blood samples are collected at three time points: pre-, immediately post, and 2-hour post bowling/rest.

Interventions

  • Behavioral Exercise
    During the bowling trial, participants perform 8 sets of 6 deliveries (bowl at match intensity throughout), followed by 2-hour rest. Each set is interspersed by a 3-minute randomized fielding simulation. During the control trial, participants rest throughout instead of bowling.

Primary outcome measures

  • Serum C-terminal telopeptide of type I collagen (CTX-I) concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Secondary outcome measures (7)
  • Serum N-terminal propeptide of type I collagen (PINP) concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
  • Serum parathyroid hormone (PTH) concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
  • Serum sclerostin concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
  • Serum dickkopf Wnt signaling pathway inhibitor 1 (DKK1) concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
  • Serum osteoprotegerin (OPG) concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
  • Serum irisin concentration [Time frame: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
  • Bowling speed [Time frame: Bowling speed is measured during the bowling trial.]

Eligibility criteria

Inclusion criteria

  • Healthy male
  • Aged 18 - 30
  • Cricket fast bowlers (a ball speed of \~100kmh) playing for a university team or above, such as British Universities and Colleges Sport (BUCS) or University Centre of Cricketing Excellence (UCCE)
  • Injury free for the last 3 months

Exclusion criteria

  • Diagnosed with any disease or use of any medication that affects bone turnover
  • Fracture experienced within the previous year/season

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Non-randomized
Model
Crossover
Masking
Open label
Primary purpose
Basic science

Study locations

United Kingdom · 1 center
  • Loughborough Univeristy — Loughborough

Identifiers

NCT: NCT07260318 · 11201

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗