Prediabetes and Metabolic Parameters Among Young Adults at Assiut University Hospital
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: No intervention.
- Who it may be relevant to
- Registry conditions: PreDiabetes. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Prediabetes Among Young Adults and Its Relation to Metabolic Parameters in Persons Attending Assuit University Hospital
Overview
Prediabetes is a major public health problem that increases the risk of developing type 2 diabetes mellitus and cardiovascular complications. Young adults represent an important age group in which early detection and intervention may prevent progression of the disease. The present study aims to identify factors associated with prediabetes and metabolic complications, and classify individuals based on clinical and biochemical profiles according to insulin resistance, dyslipidemia and fatty liver. This is an observational, cross-sectional study that will be conducted at Assiut University Hospital. Data will be collected through clinical examination, laboratory investigations, and assessment of metabolic profiles.
Interventions
- Other No intervention
Participants will be classified into groups based on impaired fasting glucose, impaired post-prandial glucose, or impaired HbA1c according to ADA criteria
Primary outcome measures
- Correlation between prediabetes subtypes and metabolic syndrome [Time frame: At baseline (cross-sectional assessment during enrollment).]
Secondary outcome measures (1)
- Factors affecting the correlation between prediabetes phenotypes and metabolic abnormalities (age, gender, family history, body physique, waist circumference and physical activity. [Time frame: At baseline (cross-sectional assessment during enrollment)]
Eligibility criteria
Inclusion criteria
- adults diagnosed with prediabetes
Exclusion criteria
- previous diagnosis of overt diabetes
- other causes of CKD (e.g. urinary tract infection)
- other causes of liver disease (e.g. HBV infection),
- use of medications that alter glucose or lipid metabolism (e.g. corticosteroids),
- current pregnancy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- http://doi.org/10.1007/s00125-013-2902-4
- http://doi.org/10.1136/bmj.g4485
- http://doi.org/10.1007/s00125-009-1443-3
- http://doi.org/10.2337/dc08-1264
- http://doi.org/10.1016/j.diabres.2007.05.004
- http://doi.org/10.2337/diabetes.52.6.1475
- http://doi.org/10.1136/bmj.i5953
- http://doi.org/10.1056/NEJMoa012512
Identifiers
NCT: NCT07259954 · AUH-MED-PREDIAB-2025