Feasibility and Safety of Blood-Flow-Restriction Training in Patients With Hemophilia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Control, BFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out).
- Who it may be relevant to
- Registry conditions: Hemophilia. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Blood Flow Restriction Training on the Subjective Perception of Pain in Hemophilic Arthropathy of the Knee Joint
Overview
In the course of a cross-over study design, 12 patients with hemophilic arthropathy will perform a training load on the knee extensor muscles. The subjects will each perform one intervention with blood flow restriction and one with a Sham-BFR intervention.
Interventions
- Device Control
Sham-BFR Exercise (20mmHg) while Leg Press Exercise (4 Sets, All out) - Device BFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out)
BFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out)
Primary outcome measures
- Pain threshold [Time frame: Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention]
- Quality of Life Score [Time frame: Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention]
Eligibility criteria
Inclusion criteria
- patients with haemophilia
- Ability for an exercise intervention
Exclusion criteria
- Sickle Cell Anemia
- Intravascular stents/bypasses
- Open Wounds/Infections of the lower extremity
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Germany · 1 center
- University Hospital Bonn — Bonn
Identifiers
NCT: NCT07259356 · 2024_H