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Recruiting NCT07248124

Pilot Study, Aimed at Describing in Myography, the Collapse of the Muscular Response Visualized in the Scratch Collapse Test, in Carpal Tunnel Syndrome.

No phase Interventional Carpal Tunnel Syndrome (CTS)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: electromyograph, Scratch Collapse Test.
Who it may be relevant to
Registry conditions: Carpal Tunnel Syndrome (CTS). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Pilot Study, Aimed at Describing in Myography, the Collapse of the Muscular Response Visualized in the Scratch Collapse Test, in Carpal Tunnel Syndrome

Overview

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve tunnel syndromes. It first involves applying a sensory stimulus to the skin over the suspected nerve compression point, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the healthy side. This loss of strength is transient and disappears after a few seconds. This test can be performed during a patient's clinical examination, with the physician assessing strength or, conversely, muscle collapse. However, while several articles have described the relevance of this test, as well as its sensitivity and specificity, no study has specifically investigated and measured this observed loss of eccentric muscle tone and its unilateral and transient nature, even though the phenomenon of CSP (cutaneous silent period) has been described. We therefore propose to analyze the myographic tracing obtained in patients diagnosed with unilateral carpal tunnel syndrome. A transient loss of muscle tone is expected by selective needle myography on the pathological side after cutaneous sensory stimulation of the wrist, while cutaneous sensory stimulation on the healthy side does not alter the tracings obtained by myography.

Interventions

  • Procedure electromyograph
    This examination uses electrodes placed along the path of the median nerve to measure the transmission of nerve impulses (conduction studies). It is performed on both hands to compare the results.
  • Diagnostic test Scratch Collapse Test
    The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve canal syndromes. It involves first performing a sensory stimulus on the skin at the suspected nerve compression site, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the stimulated side.

Primary outcome measures

  • Evolution of the myographic tracings [Time frame: one day]

Eligibility criteria

Inclusion criteria

  • Patient over 18 years old
  • Patient with clinical unilateral carpal tunnel syndrome diagnosed by history, clinical examination and electromyography,
  • Patient who has been informed and has given their free, informed, and written consent,
  • Patient affiliated with or beneficiary of a social security scheme.

Exclusion criteria

  • Other associated canal syndrome on either side (ulnar, defilement, lacertus),
  • Rotator cuff pathology, insufficiency or rupture of the infraspinatus,
  • Associated cervical pathology,
  • Neuropathy, central or peripheral neurological disease,
  • Diabetic patient,
  • Patient with cognitive impairments that prevent the understanding of the study information,
  • Refusal to participate in the study,
  • Pregnant, parturient, or breastfeeding woman,
  • Patient under legal protection,
  • Patient not receiving health protection,
  • Protected patient: adult under guardianship, curatorship, or other legal protection, deprived of liberty by judicial or administrative decision

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Other

Study locations

France · 1 center
  • Clinique de l'Ormeau — Tarbes

Identifiers

NCT: NCT07248124 · SC-My · 2025-A01019-40

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗