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Not yet recruiting NCT07246720

IPP-PSP Block vs. SPSIPB in Breast Surgery

No phase Interventional Postoperative Acute Pain Breast Cancer Regional Anesthesia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Interpectoral-Pectoserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block.
Who it may be relevant to
Registry conditions: Postoperative Acute Pain, Breast Cancer, Regional Anesthesia. Basic parameters: 18 years — 65 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Interpectoral-pectoserratus Plane Block vs. Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia in Patients Undergoing Breast Cancer Surgery

Overview

This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in patients undergoing breast cancer surgery. Both techniques are ultrasound-guided regional anesthesia methods targeting different interfascial planes of the thoracic wall. The study will evaluate postoperative pain scores, opioid consumption, Quality of recovery and potential complications. The findings are expected to contribute to optimizing regional anesthesia strategies for enhanced recovery and improved analgesia following breast cancer surgery.

Interventions

  • Procedure Interpectoral-Pectoserratus Plane Block
    Ultrasound-guided injection between pectoralis major-minor and pectoralis minor-serratus anterior planes.
  • Procedure Serratus Posterior Superior Intercostal Plane Block
    Ultrasound-guided injection between the serratus posterior superior muscle and the intercostal muscles.

Primary outcome measures

  • Cumulative opioid consumption [Time frame: in the first 24 hours after completion of the surgical procedure]
Secondary outcome measures (2)
  • Postsurgical Quality of Recovery measured by the Quality of Recovery questionnaire [Time frame: first day after surgery]
  • Number of episodes of postoperative pain [Time frame: In the first 24 hours after completion of the surgical procedure]

Eligibility criteria

Inclusion criteria

  • 18-65 years of age
  • ASA I-II-III risk groups
  • Patients with informed consent
  • Patients undergoing breast cancer surgery

Exclusion Criteria: • Ages <18 and >65

  • ASA ≥ IV
  • History of allergy to local anesthetics
  • Known coagulation disorders
  • Infection near the insertion site
  • Chronic analgesic use
  • Patients with diabetes mellitus and those receiving neoadjuvant chemotherapy (due to potential impairment of pain sensation)
  • Body mass index >30
  • Dementia or confusion
  • Lack of cooperation

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • Zonguladk Bulent ecevit University — Zonguldak

Identifiers

NCT: NCT07246720 · 2025/16-9

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗