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Recruiting NCT07244146

Effects of CHRIST Among Children With Spastic CP

No phase Interventional Cerebral Palsy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: CHRIST.
Who it may be relevant to
Registry conditions: Cerebral Palsy. Basic parameters: 6 years — 12 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effects of Comprehensive Hand Intense Strength Training on In Hand Manipulation and Grip Strength Among Children With Spastic Cerebral Palsy

Overview

This Quasi experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength amonfg children with Spastic Cerebral Palsy. The study involves 14 children from 6-12 years of age, and will be given intervention for 10 weeks period. Key performance outcomes- In Hand Manipulation and Grip Strength will be assessed both before and after the intervention. This study aims to address this gap by evaluating the effects of the CHRIST on IHM and grip strength in children diagnosed with spastic cerebral palsy. The hypothesis is that integrating strength training with high repetition, functionally relevant tasks yields greater and more practical gains than strength training or conventional therapy alone. Data will be analyzed through SPSS version 27.0

Detailed description

This Quasi Experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength in children with Spastic Cerebral Palsy. CHRIST was designed to enhance the motor ability of children. The efficacy of this program will be investigated through a Quasi Experimental study. Data will be collected from special schools and rehabilitation centers having children with spastic cerebral palsy. The intervention CHRIST will be given thrice a week for forty minutes. The study will be completed in 10 weeks after approval of the synopsis. The study will include 14 children, male and female. Inclusion criteria for the study will include patients diagnosed with spastic CP. Data will be collected from children aged 6 to 12 years old. IHM will be measured by Melbourne Assessment 2 scale (MA2). Grip Strength will be measured by dynamometer. IHM \& Grip Strength will be assessed both before and after the intervention.This study aims to address this gap by evaluating the effects of CHRIST on IHM and grip strength in children diagnosed with spastic cerebral palsy. The hypothesis is that integrating strength training with high repetition, functionally relevant tasks yields greater and more practical gains than strength training or conventional therapy alone. Data will be analyzed through SPSS version 27.0

Interventions

  • Other CHRIST
    CHRIST, is a treadmill-based training with body weight supported by the upper limbs. There will be a session of 40 minutes, which includes 3 sets (10 minutes exercise with 3 minutes rest period per set), three times a week, over a 10 week period. By maintaining the posture of the quadruped, the abdomen and weight of the lower limb will be supported by using a support board under the abdomen. The speed of the treadmill for the upper limbs will be 0.3-1.2 km/h.

Primary outcome measures

  • Jamma Dynamometer [Time frame: Baseline, 1st week and 10th week]
Secondary outcome measures (1)
  • Melbourne assessment 2 (MA2) [Time frame: Baseline, 1st week and 10th week]

Eligibility criteria

Inclusion criteria

  • Children Diagnosed with hemiplegic spastic cerebral palsy.
  • Age 6-12 years.
  • Capable of following commands regarding hand use and testing.
  • Capable of communicating needs.
  • Parents or caregivers willing to provide informed consent and participate in the study.
  • No contraindications to moderate physical activity.
  • Able to lift the more affected arm 15 cm above a table surface and grasp light objects

Exclusion criteria

  • Children with musculoskeletal system injuries, including upper limb fractures or contractures, as well as those who had received medications affecting muscle strength or spasticity, were excluded from the study.
  • Orthopedic surgery involving the more affected hand within the past 6 months.
  • Children with Cardiovascular disease.
  • Lack of cooperation with instructions or other behavioral challenges that prevent effective delivery of intensive therapy.
  • Visual impairments that may hinder active participation.
  • Seizure or family history of seizure disorders

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Other

Study locations

Pakistan · 1 center
  • Imran Amjad — Lahore

Publications

  • Lee DR, You JH, Lee NG, Oh JH, Cha YJ. Comprehensive Hand Repetitive Intensive Strengthening Training (CHRIST)-induced morphological changes in muscle size and associated motor improvement in a child with cerebral palsy: an experimenter-blind study. NeuroRehabilitation. 2009;24(2):109-17. doi: 10.3233/NRE-2009-0460. PMID 19339750

Identifiers

NCT: NCT07244146 · REC/RCR&AHS/FAIRY ALI

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗