Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Vascular Filling, Newborn, Weight Loss, Jaundice. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the pre-delivery phase, such as pre-partum maternal fluid intakes, and the subsequent feeding method chosen for the newborn infant. This study aimed at exploring the association between maternal vascular fluid loading during labor in the pre-partum period and neonatal weight loss in the first two days of life. The study focuses on infants fedded with infant formula. This observational, retrospective, single-center study was carried out at the Amiens University Hospital Center. The participants were mothers aged 18 and older, hospitalized in the maternity ward following full-term delivery (\> 37 weeks of gestation). Data were collected through the medical records of the patient and their newborn. The investigators hypothesize that a relationship may exist between maternal pre-partum vascular fluid loading and neonatal weight loss in the first two days of life, in infants fed with infant formula. These results could raise awareness and help adapt medical and parental approaches to neonatal weight loss.
Primary outcome measures
- Correlation between maternal vascular fluid loading and newborn infant weight loss [Time frame: 2 days]
Secondary outcome measures (2)
- Correlation between maternal vascular fluid loading and respiratory distress [Time frame: 2 days]
- Correlation between maternal vascular fluid loading and jaundice of the newborn [Time frame: 2 days]
Eligibility criteria
Inclusion criteria
- Full-term delivery (≥37+0 SA)
- Singleton pregnancy
- Mother over 18 years of age
- Infant formula feeding exclusively in the maternity ward for the first 2 days
Exclusion criteria
- Mother under guardianship
- Mother who does not understand French
- Mother objecting to her personal data being reused for research purposes
- Incomplete or incorrectly completed patient medical record
- Mixed or exclusive breastfeeding
- Mother presenting a hemodynamic disorder in the 12 hours preceding delivery, requiring a filling specifically for this reason
- Child with renal pathology or uropathy
- Children with cleft lip, palate or labio-palate
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
France · 1 center
- CHU Amiens Picardie — Amiens
Identifiers
NCT: NCT07243054 · PI2025_843_0037