Comparison Between Modified Periosteal Inhibition (MPI) and Flapless Immediate Implant Placement
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Immediate implant placement via flapless approach, Immediate implant placement in conjunction with modified periosteal inhibition technique using collagen sponge in the gap distance, Immediate implant placement in conjunction with modified periosteal inhibition technique using cortico-cancellous bone allograft in the gap distance.
- Who it may be relevant to
- Registry conditions: Non-restorable Posterior Teeth, Thin Buccal Bone Plate, Buccal Bone Fenestraion. Basic parameters: 20 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Impact of Modified Periosteal Inhibition Technique on Alveolar Bone Stability in Immediate Implant Placement Procedures (Randomized Controlled Clinical Trial)
Overview
To clinically and radiographically assess the impact of the modified periosteal inhibition (MPI) technique, applied during immediate post-extraction implant placement, on alveolar bone dimensional changes, in comparison to the conventional flapless immediate implant approach.
Detailed description
To assess the impact of the modified periosteal inhibition (MPI) technique, applied during immediate post-extraction implant placement in comparison to the conventional flapless immediate implant approach on radiographically by assessing marginal bone level measurements and bucco-lingual alveolar width. Clinically, pain levels, wound healing index, primary, secondary implant stability measured by resonance frequency analysis (RFA), peri-implant probing depth, and pink esthetic score (PES) will be assessed.
Interventions
- Procedure Immediate implant placement via flapless approach
Implant site preparation will be performed flapless using 3D computer assisted planned surgical stent. Implant site preparation will be performed using commercially available standard surgical kit. A single customized screw-type healing abutment will be screwed to the implant. Cortico-cancellous bone allograft will be inserted inside the extraction socket in the gap distance between the implant and surrounding alveolar bone of the fresh extraction socket. - Procedure Immediate implant placement in conjunction with modified periosteal inhibition technique using collagen sponge in the gap distance
After papillae incisions, an intra-sulcular incision will be made on the vestibular side of the extraction socket, extending to the mesial and distal mid-tooth with a #15c surgical scalpel. Implant site preparation will be performed using 3D computer assisted planned surgical stent. Implant site preparation will be performed using a standard surgical kit. A single customized screw-type healing abutment will be screwed to the implant. A full-thickness flap will be elevated creating a room that wo - Procedure Immediate implant placement in conjunction with modified periosteal inhibition technique using cortico-cancellous bone allograft in the gap distance
After papillae incisions, an intra-sulcular incision will be made on the vestibular side of the extraction socket, extending to the mesial and distal mid-tooth with a #15c surgical scalpel. Implant site preparation will be performed using 3D computer assisted planned surgical stent. Implant site preparation will be performed using a standard surgical kit. A single customized screw-type healing abutment will be screwed to the implant. A full-thickness flap will be elevated creating a room that wo
Primary outcome measures
- Radiographic evaluation of horizontal and vertical dimensional changes of the alveolar bone placement by using cone beam computed tomography (CBCT). [Time frame: Baseline, 6 months, 12 months after the implant placement]
Secondary outcome measures (5)
- Pain Index [Time frame: first post-operative day, third day and after one week.]
- Wound Healing Index (WHI) [Time frame: 1 and 2 weeks after surgery]
- Implant Stability Measurements [Time frame: The RFA measurements will be made immediately after implant installation, and 3 months after implant placement before the prosthetic phase.]
- Peri-implant Probing Depth (PPD) [Time frame: Baseline, 6 months and 12 months post-operatively.]
- Esthetic Evaluation [Time frame: At the time of prosthetic phase (3 months after implant placement), 6 months, and 12 months postoperatively]
Eligibility criteria
Inclusion criteria
- Patient's age ranges between 20 and 50 years including both genders.
- General good health (American Society of Anesthesiologists I-II).
- Presence of one hopeless non-restorable tooth requiring extraction at the posterior region.
- Adequate amount of palatal bone and basal bone (≥ 3 mm) to engage the immediately placed implants.
- Adequate keratinized soft tissue.
- Thick gingival phenotype (˃ 1.5 mm).
- Thin buccal bone plate or presence of fenestration.
- Favorable pattern of occlusion.
- Patient who is able to understand and sign a written consent.
Exclusion criteria
- Pregnancy or lactating females.
- Untreated periodontitis.
- Acute dentoalveolar infection.
- Complete absence of buccal bone plate.
- Osteometabolic disease.
- Chemotherapy or radiation therapy history of the neck-head area within the past 12 months.
- Heavy smokers (>20 cigarettes/per day) according to WHO.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of Dentistry, Mansoura university — Al Mansurah
Identifiers
NCT: NCT07238738 · MPI with immediate implant