Revascularization of Young Immature Permenant Teeth Using Different Types of Intra Canal Medication
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Grape Seed Extract, Glycyrrhizin, Triple Antibiotic Paste.
- Who it may be relevant to
- Registry conditions: Traumatic Teeth, Necrotic Teeth. Basic parameters: 7 years — 13 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of the Effect of Grape Seed Extract, Glycyrrhizin Compared to Triple Antibiotic Paste as Intra Canal Medication in Revascularization of Necrotic Permanent Immature Teeth in Children: A Randomized Clinical Trial
Overview
Evaluation of the Effect of Grape Seed Extract, Glycyrrhizin Compared to Triple Antibiotic Paste as Intra Canal Medication in Revascularization of Necrotic Permanent Immature Teeth in Children: A Randomized Clinical Trial
Detailed description
Digital count of e.faecalis before and after application of different type of intra canal medication
Interventions
- Drug Grape Seed Extract
Grape seed extract in form of hydrogel with concentration 6.5 % left in canal for one week - Drug Glycyrrhizin
Glycyrrhizin hydrogel 50 micrograms in 1 milligram left in canal for one week - Drug Triple Antibiotic Paste
Trple antibiotic paste Left for one week
Primary outcome measures
- Digital count of e.faecalis [Time frame: After One week of mediation application]
- Clinical evaluation success will be assessed using following criteria of success according to scoring system Absence of : - Pain, - Soft tissue swelling - soft tissue inflammation - Sinus tract - tenderness to percussion - tooth mobility [Time frame: After one week of mediation application]
Secondary outcome measures (1)
- Radiographic evaluation [Time frame: After tweleve month]
Eligibility criteria
Inclusion criteria
- Healthy children aged from 7-13 years old.
- Patient with necrotic pulp.
- Open apex.
Exclusion Criteria:.
- Teeth with root fractures.
- Presence of root resorptions.
- Presence of periodontal pockets.
- Developmental anomalies.
- Tooth with class III mobility
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Al-Azhar University faculty of dental medicine — Cairo
Publications
- Evaluation of the Effect of Grape Seed Extract, Glycyrrhizin Compared to Triple Antibiotic Paste as Intra Canal Medication in Revascularization of Necrotic Permanent Immature Teeth in Children: A Randomized Clinical Trial
Identifiers
NCT: NCT07236567 · Revascularization