A RCT of Moist Ag Dressing in Chronic Wound
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Ag foam dressing named MepilexAg, Dry Ag dressing.
- Who it may be relevant to
- Registry conditions: Chronic Wound, Hard to Heal Wounds, Dressing, Wound he'a'Ling. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Dry Versus Moist Ag Dressings for Local Wound Infections: A Randomized Controlled Trial on Effectiveness and Cost-Effectiveness
Overview
This study aims to explore the differences in efficacy and cost-effectiveness between self-adhesive soft polysilicone silver ion foam dressings and traditional silver dressings in local infected wounds through a prospective randomized controlled study. The goal is to provide evidence-based medical support for clinical application, further shorten the wound healing time, and reduce the economic burden on the medical system and patients.
Interventions
- Device Ag foam dressing named MepilexAg
Using MepilexAg in conjunction with conventional clinical treatments in chronic local infectious ulcer - Device Dry Ag dressing
Using dry Ag dressing in conjunction with conventional clinical treatments
Primary outcome measures
- wound area reduction in two weeks [Time frame: From enrollment to the end of treatment at 2 weeks]
Secondary outcome measures (1)
- wound healing rate [Time frame: From enrollment to the end of treatment at 2 weeks]
Eligibility criteria
Inclusion criteria
- The patient's age ranges from 18 to 80 years old.
- According to the IWII wound infection staging, infected wounds are classified as local infections\*.
- The wound type is ulcer, with an ulcer area ranging from 1 to 40 cm².
- The wound stage is in the necrosis stabilization phase, granulation growth phase, or epithelial crawling phase\*\*.
- Voluntary participation in this study and signing the informed consent form
Exclusion criteria
- Severe diseases such as acute myocardial infarction, heart failure, hepatitis, shock, and respiratory failure have not been corrected yet;
- The blood sugar level of diabetes is out of control, with fasting blood sugar > 15 mmol/L and glycosylated hemoglobin ≥ 10%;
- There is active bleeding in the wound, and the conventional basic treatment plan cannot be implemented;
- Serum albumin < 20 g/L; hemoglobin < 60 g/L; platelets < 50 × 109/L;
- Disseminated infection or systemic infection state, and antibiotics are being used or will be used for treatment;
- Patients with advanced malignant tumors;
- The patient is in the active stage of autoimmune diseases;
- The patient has previously been allergic to self-adhesive soft polysilicone silver ion foam dressings (Meipikang Silver) or Anxidean Nano Silver Trauma Patch;
- The patient cannot cooperate or has a mental disorder;
- According to the investigator's judgment, the subject has clear reasons that affect wound healing and is not suitable for this study or cannot comply with the requirements of this study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Peking University Third Hospital — Beijing
Identifiers
NCT: NCT07235254 · Long2025-CW-Ag foam dressing