Menu
Recruiting NCT07228650

ADHD Remote Technology and ADHD Transition: Predicting and Preventing Negative Outcomes

— Observational Attention Deficit Hyerpactivity Disorder

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Attention Deficit Hyerpactivity Disorder. Basic parameters: 16 years — 17 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United Kingdom
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental condition affecting 5.9% of young people. Late adolescence can be a particularly challenging period for young people with ADHD, with major life transitions, new demands and increased expectations. This vulnerable phase also coincides with the transition from child and adolescent mental health care to adult ADHD services, where new UK data show that most young people with ADHD do not successfully transfer to adult services. Therefore, many young people with ADHD do not receive appropriate interventions at a time when they may need them most. Opportunities for intervention are currently not fully realised due to both the young people's disengagement from clinical services and our limited understanding of real-world targets for more holistic interventions. The current study seeks to address these needs using remote (not in-person) measurement technology (RMT). The MRC-funded project, ART-transition, will use the ADHD Remote Technology ('ART') assessment and monitoring assessments with young people with a diagnosis of ADHD aged 16-17 and the RADAR-base mobile-health platform to which it is linked. ART consists of active (e.g. questionnaires) and passive (e.g. sleep) smartphone app monitoring. In the study, the investigators will address three questions on the transition to adulthood for individuals with ADHD: what changes take place, what predicts them, and how can the investigators prevent negative outcomes and support healthy lifestyles? The investigators will remotely monitor 250 young people with ADHD over two years. The investigators will then co-design, with young people with ADHD, a prototype for a new ADHD-transition smartphone app. Our approach focuses on giving young people with ADHD greater autonomy in how they manage their ADHD, in collaboration with their clinician, and places the emphasis on modifiable environmental factors and the prevention of negative outcomes.

Primary outcome measures

  • ADHD symptoms and functional impairment [Time frame: Baseline and every 4 weeks up to month 24]
  • ADHD symptoms [Time frame: Baseline and every day up to month 24]
  • Anxiety (General Anxiety Disorder-7, GAD-7) [Time frame: Baseline and every 4 weeks up to month 24]
  • Depression (Patient Health Questionnaire -8, PHQ-8, adapted) [Time frame: Baseline and every 4 weeks up to month 24]
  • Aggression (Reactive-Proactive Aggression Questionnaire for Adults. RPQ-A, adapted) [Time frame: Baseline and every 4 weeks up to month 24]
  • Irritability - (Affective Reactivity Index self-report, ARI-s, adapted) [Time frame: Baseline and every 4 weeks up to month 24]
  • Nicotine Dependence - The Fagerstrom Test for Nicotine Dependence [Time frame: Baseline and every 4 weeks up to month 24]
  • Alcohol Use (Alcohol Use Disorders Identification Test questionnaire, AUDIT) [Time frame: Baseline and every 4 weeks up to month 24]
  • Eating Disorders (Short Form of the Eating Disorder Examination Questionnaire, EDE-QS) [Time frame: Baseline and every 6 months up to month 24]
  • Self-esteem (Rosenberg Self-Esteem Scale, RSES) [Time frame: Baseline and every 6 months up to month 24]

Eligibility criteria

Inclusion criteria

  • Diagnosis of DSM-5 ADHD
  • Aged 16-17
  • Able to give informed consent for participation
  • Willing and able to complete self-reported assessments via smartphone
  • Willing to use either their own compatible Android phone or a study Android - phone as their only smartphone during the data collection period
  • Willing to wear the wearable device during the data collection period

Exclusion criteria

  • Psychosis, currently experiencing a major depressive episode, mania, drug dependence in the last six months, or a major neurological disorder.
  • Recent contact with psychiatric acute care (admission, crisis team or liaison team (A\&E) in the last six months
  • Any other major medical disease which might impact upon the patient's ability to participate in normal daily activities (e.g., due to hospitalisations)
  • Pregnancy
  • IQ < 70

Informant Inclusion Criteria:

  • A parent or guardian, as chosen by the participant with ADHD
  • Aged 18 or over
  • Willing and able to complete web-based questionnaires regarding the participant with ADHD

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United Kingdom · 1 center
  • King's College London — London

Identifiers

NCT: NCT07228650 · 334427

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗