Biofilm on Chest Drains After Thoracic Surgery: Clinical Impact and Antibiotic Resistance
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Chest Drain Tip Sampling.
- Who it may be relevant to
- Registry conditions: Biofilms, Thoracic Surgery, Postoperative Infection, Antibiotic Resistance, Bacterial. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Biofilm Formation on Thoracic Drains: Clinical Significance and Association With Antibiotic Resistance
Overview
This prospective observational study aims to investigate the frequency and clinical significance of biofilm formation on thoracic chest drains used after thoracic surgery. Biofilms are structured bacterial communities that adhere to surfaces and can promote infection and antibiotic resistance. In this study, small samples from the tips of chest drains will be collected under sterile conditions at the time of drain removal and analyzed in the microbiology laboratory. The main objectives are to evaluate the relationship between the duration of chest drain placement and the presence of biofilm, and to identify the antibiotic resistance profiles of microorganisms isolated from these biofilms. Secondary outcomes include the association between biofilm formation, postoperative infections (such as empyema or wound infection), and the length of hospital stay. This study will be conducted at Ondokuz Mayıs University Faculty of Medicine, Department of Thoracic Surgery, in collaboration with the Department of Microbiology. The findings are expected to contribute to better understanding of optimal drain management and infection prevention strategies after thoracic surgery.
Interventions
- Other Chest Drain Tip Sampling
No active intervention; routine chest drain removal followed by microbiological and biofilm analysis of drain tip samples.
Primary outcome measures
- Presence and Intensity of Biofilm Formation on Chest Drain Tips [Time frame: At the time of chest drain removal (postoperative days 1-7)]
Eligibility criteria
Inclusion criteria
- Age 18 years and older
- Undergoing elective thoracic surgery requiring chest drain placement
- Able and willing to provide written informed consent
Exclusion criteria
- Presence of active infection prior to surgery
- Emergency thoracic surgery
- Immunosuppressed patients (e.g., neutropenia, advanced malignancy, organ transplantation)
- Patients receiving systemic antibiotic therapy at the time of drain removal
- Drainage for empyema or pre-existing pleural infection
- Presence of extrathoracic infection focus
- Refusal or inability to provide informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Ondokuz Mayis University Medical Faculty, Department of Thoracic Surgery — Samsun
Identifiers
NCT: NCT07228598 · B.30.2.ODM.0.20.08/600-660