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Recruiting NCT07225491

Spine Oncology Registry

Observational Spine Tumor Spine Metastases Spine Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Spine Tumor, Spine Metastases, Spine Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Prospective Registry of Patients Undergoing Surgical Decompression Followed by Radiation Therapy for Spine Tumors

Overview

This is an observational study to evaluate hardware related and oncologic outcomes in adult patients with primary and metastatic spine disease undergoing separation surgery followed by radiation treatment.

Detailed description

This study is being done to collect information about patients undergoing separation surgery followed by radiation for the treatment of primary and metastatic spine disease. Participants will be asked to complete some patient reported outcome questionnaires and researchers will collect information from medical records to evaluate oncologic and hardware related outcomes.

Primary outcome measures

  • Overall survival [Time frame: 12, 18, 24 months]
  • Local control of treated lesion based on radiographic review [Time frame: 3, 6, 9, 12, 15, 16, 21, 24 months]
  • Progression free survival [Time frame: 3, 6, 9, 12, 15, 16, 21, 24 months]

Eligibility criteria

Inclusion criteria

  • Diagnosis of primary or metastatic disease to the spine who undergo surgical decompression and stabilization followed by radiation therapy

Exclusion criteria

  • Inability to obtain a standard MRI or CT / CT myelogram for radiation treatment planning and dosimetry
  • Inability to receive radiation treatment.
  • Patients under 18 years of age

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 3 centers
  • University of Michigan — Ann Arbor
  • Rutgers Robert wood Johnson Medical School — New Brunswick
  • The Ohio State University Wexner Medical Center — Columbus

Identifiers

NCT: NCT07225491 · 20253216 · NCI-2024-07629 · OSU-23207

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗