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Recruiting NCT07220668

Sense4Safety Intervention

Phase I / Phase II Interventional Mild Cognitive Impairment

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Sense4Safety.
Who it may be relevant to
Registry conditions: Mild Cognitive Impairment. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Falls and fall-related injuries are significant public health issues for adults 65 years of age and older. Over a third of older adults (OA) fall each year and 10-20% of falls result in serious injuries such as fractures and head trauma. The annual direct medical costs in the US as a result of falls are estimated to exceed $50 billion, and this estimate does not include the indirect costs of disability, dependence, and decreased quality of life. This project targets community dwelling OA with mild cognitive impairment (MCI). MCI is a leading risk factor for falls in OA. Approximately 15%-20% of OA have MCI, and over 60% of OA with MCI fall annually - two to three times the rate of those without cognitive impairment. We have developed and pilot-tested an innovative technology-supported intervention called Sense4Safety to 1) identify escalating risk for falls real-time through in-home passive sensor monitoring; 2) employ machine learning to inform individualized alerts for fall risk; and 3) link 'at risk' older adults with a coach who will guide them in implementing evidence-based individualized plans to reduce fall-risk. The purpose of this study is to assess the effectiveness of Sense4Safety in reducing fall risk with a randomized clinical trial, and understand implementation factors to improve the scalability of Sense4Safety in diverse community settings.

Interventions

  • Behavioral Sense4Safety
    Sense4Safety is a technology-enhanced intervention that includes multiple components: 1) in-home assessment; 2) tailored education and exercise; 3) passive monitoring and communication. The intervention is primarily via video-conferencing or phone, supplemented by in-home visits at intake, and 6 months to conduct in-person assessments.

Primary outcome measures

  • Gait Speed [Time frame: 0, 3 and 6 months]
  • Lower extremity strength and functional mobility [Time frame: 0, 3, 6 mos.]
  • Functional mobility and fall risk [Time frame: 0, 3, 6 mos.]
  • Static balance in narrow stance positions [Time frame: 0, 3, 6 mos.]
Secondary outcome measures (1)
  • Fear of Falling [Time frame: 0, 3, 6 mos.]

Eligibility criteria

Inclusion criteria

  • aged ≥ 65 years
  • reside in senior living communities and plan to be in the area for more than 6 months
  • be able to walk household distances
  • score of at least 1 of 12 on the Short Physical Performance Battery (SPPB)
  • meet MCI criteria (MCI is defined as a score ≥17 Montreal Cognitive Assessment)

Exclusion criteria

Exclusion criteria include terminal illness, central nervous system condition such as stroke or Parkinson's disease, diagnosis of dementia, severe vision or hearing deficits, and reliant on wheelchair or scooter within living quarters.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Prevention

Study locations

United States · 1 center
  • University of Pennsylvania — Philadelphia

Identifiers

NCT: NCT07220668 · GM1XX56LEP58 · 1R01AG090377-01A1

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗