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Deviated Nasal Septum Effect on Maxillary Sinus Volumes and Development of Maxillary Sinusitis by CT

Observational Deviated Nasal Septum and Maxillary Sinusitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Deviated Nasal Septum and Maxillary Sinusitis. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Effect of Nasal Septal Deviation on Maxillary Sinus Volumes and Development of Maxillary Sinusitis :A CT Study.

Overview

By using CT of the nose and paranasal sinuses, we'll study the effect of nasal septum deviation on maxillary sinus volumes, assess the association between the severity and type of nasal septum deviation and the occurrence of maxillary sinusitis and compare the maxillary sinus volume on the deviated side with that of the contralateral side.

Primary outcome measures

  • CT based comparison in cases with deviated nasal septum [Time frame: Baseline]

Eligibility criteria

Inclusion criteria

  • Age ≥18 years.
  • Availability of high-resolution CT scans of paranasal Sinuses (axial, coronal, sagittal views).
  • Adequate imaging quality allowing sinus volumetry and septal deviation measurement.
  • Anatomical landmarks visible: Crista galli, hard palate, choanae, uncinate process/OMC region clearly identifiable to permit NSD measurement and sinus segmentation.

Exclusion criteria

  • Age < 18 years.
  • Previous sinonasal or maxillofacial surgery.
  • History of facial trauma or fractures affecting the nasal septum or sinus walls.
  • Sinonasal tumors, polyps, or large cysts.
  • Congenital craniofacial anomalies (e.g., cleft palate).
  • head and neck syndromes.
  • Cases with systemic diseases affecting growth and development.

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Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Publications

  • Razavi M, Shams N, Pirasteh SMA. Determining the effects of deviated nasal septum on maxillary sinus volume using cone-beam computed tomography. Immunopathol Persa. 2023;9(1):e34427
  • Elahi MM, Frenkiel S, Fageeh N. Paraseptal structural changes and chronic sinus disease in relation to the deviated septum. J Otolaryngol. 1997 Aug;26(4):236-40. PMID 9263892
  • Serifoglu I, Oz II, Damar M, Buyukuysal MC, Tosun A, Tokgoz O. Relationship between the degree and direction of nasal septum deviation and nasal bone morphology. Head Face Med. 2017 Feb 28;13(1):3. doi: 10.1186/s13005-017-0136-2. PMID 28245851

Identifiers

NCT: NCT07210827 · CT in nasal septal deviation

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗