Menu
Not yet recruiting NCT07209150

Randomized Controlled Trial of Different Antibiotic Duration Prior to Prostate Enucleation Surgery

Phase III Interventional BPH With Urinary Obstruction Antibiotic Prophylaxis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: antibiotic prophylaxis.
Who it may be relevant to
Registry conditions: BPH With Urinary Obstruction, Antibiotic Prophylaxis. Basic parameters: from 18 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Randomized Controlled Trial of 3 vs 7 Days for Perioperative Antibiotic Prophylaxis for Patients With an Indwelling Catheter Prior to Holmium Laser Enucleation of the Prostate

Overview

To compare the risk of infectious complications (UTI, pyelonephritis, sepsis, hospital admission, ED visits) for patients with an indwelling urinary catheter (urethral or suprapubic) or CIC receiving 3 or 7 days of peri-operative antibiotic prophylaxis at time of Holmium Laser Enucleation of the Prostate

Interventions

  • Drug antibiotic prophylaxis
    we will compare varying durations of antibiotic prophylaxis prior to prostate enucleation surgery

Primary outcome measures

  • Infectious complications [Time frame: 0-90 days postoperatively]
Secondary outcome measures (1)
  • healthcare utilization [Time frame: 0-90days]

Eligibility criteria

Inclusion criteria

  • 1\. Candidate for HoLEP surgery 2. Must be 18 years or older. 3. The patient must be able to understand and willing to provide informed consent as described in this study protocol.

Exclusion criteria

  • 1\. Under the age of 18 2. Refuse to provide informed consent 3. Anticipated need for perineal urethrostomy 4. History of multi-drug resistant organism on urine culture that is not susceptible to any oral agents

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Prevention

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07209150 · 2025HoLEP_periopabx

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗