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Recruiting NCT07207863

Tianshan Community Cohort Establishment and Follow-up

— Observational Cohort Study Natural Population Northwest Region of China

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Cohort Study, Natural Population, Northwest Region of China. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

The Cardiac and Panvascular Medicine Diagnosis and Treatment Center, People's Hospital of Xinjiang Uygur Autonomous Region,

Overview

This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.

Detailed description

This research is conducted through population-based health examinations among residents in northwest China. By providing annual health assessments, structured health education, and community-based health promotion activities, the study aims to enhance health awareness, identify determinants of disease, implement targeted interventions to improve lifestyle behaviors, reduce modifiable risk factors, and promote overall community health.

The cohort integrates data from multiple sources- including health assessments, electronic health records, mortality registries, statistical yearbooks, and environmental datasets- encompassing a wide range of health-related information, such as demographics, lifestyle factors, family and personal medical histories, living conditions, enrollment in national public health services, physical examinations, laboratory tests, diagnostic assessments, disease outcomes, and cause-specific mortality. Event-driven follow-up data are obtained from 163 hospitals and 63 Traditional Chinese Medicine hospitals, covering all secondary and tertiary-level hospitals in the region. Inpatient data are systematically documented by qualified medical personnel and entered into an electronic health information system. All disease diagnoses are coded according to the 10th Revision of the International Classification of Diseases (ICD-10). Mortality data, including the timing and specific cause of death, are primarily obtained through local death registration systems.

Primary outcome measures

  • Mortality [Time frame: 20 years]
  • Cardiovascular diseases [Time frame: 20 years]
  • Digestive diseases [Time frame: 20 years]
  • Endocrine diseases [Time frame: 20 years]
  • Infections diseases [Time frame: 20 years]
  • Benign neoplasm or Carcinoma in situ [Time frame: 20 years]
  • Cancers [Time frame: 20 years]
  • Genitourinary diseases [Time frame: 20 years]
  • Haematological or immunological diseases [Time frame: 20 years]
  • Musculoskeletal diseases [Time frame: 20 years]

Eligibility criteria

Inclusion criteria

  • Residents >=18y
  • Permanent residents or individuals who have lived in the region for more than 5 years and are enrolled in local social security medical insurance
  • Residents without severe physical disability and capable of normal communication
  • Residents whose diseases and deaths are monitored and managed by the local health authorities
  • Residents who voluntarily participate and provide written informed consent

Exclusion criteria

  • Temporary residents or floating population
  • Residents with severe health conditions that prevent participation in the study
  • Residents who are unwilling to undergo follow-up assessments for the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

China · 1 center
  • People's Hospital of Xinjiang Uygur Autonomous Region — Ürümqi

Identifiers

NCT: NCT07207863 · Tianshan2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗