Children Acceptance of AgNP Mouthwash Against Chlorhexidine Mouthwash
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%).
- Who it may be relevant to
- Registry conditions: Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste. Basic parameters: 6 years — 12 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Comparative Assessment of Children's Acceptance and Compliance of Mouthwash Containing Silver Nanoparticles Compared to Chlorhexidine Mouthwash: A Randomized Clinical Trial.
Overview
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine.
Detailed description
Effective management of dental plaque is crucial for preventing periodontal diseases, dental caries, and other oral health complications. Oral hygiene can be maintained through both chemical and mechanical methods. Chemical methods are particularly beneficial in situations where mechanical cleaning proves challenging. Mouthwashes represent a significant chemical strategy for controlling plaque. Among different types of mouthwashes, chlorhexidine is considered the gold standard due to its high efficacy against a broad spectrum of bacteria and its role in plaque management, which helps prevent periodontal diseases. However, it is important to note that chlorhexidine has several side effects, such as numbness, changes in taste perception, dental staining, and an unpleasant bitter taste.
In modern applications, nanotechnology is being utilized more frequently, especially with the integration of nanoparticle materials. Silver nanoparticles, in particular, are widely used in the medical field because of their remarkable antibacterial effects on oral biofilms associated with periodontal disease.
Therefore, this research aims to evaluate the children's acceptance of chlorhexidine mouthwash in children compared to a mouthwash containing silver nanoparticles, as well as to assess their respective impacts on gingivitis.
Interventions
- Other nano silver mouthwash
nano silver mouthwash will reduce the side effect of chlorhexidine and increase acceptance of the mouthwash to patients - Other Chlorhexidine mouthwash (0.12%)
the concentration of chlorhexidine - Other Chlorhexidine mouthwash (0.2%)
chlorhexidine mouthwash 0.2% (orovex )
Primary outcome measures
- children acceptance and compliance [Time frame: 15 days]
Secondary outcome measures (3)
- Gingival health [Time frame: 15 days]
- plaque thickness at gingival margin [Time frame: 15 days]
- color stability of composite restoration of anterior teeth [Time frame: 15 days]
Eligibility criteria
Inclusion criteria
- Children aged from 6 to 12 in good general health and medically free
- Cooperative patient who will care about attending the follow-up visit
- Acceptance of the parents to sign the informed consent
- Composite restoration on anterior teeth Exclusion criteria
- Children who are unable to attend the follow-up visit
- Medically compromised patient
- Handi-capped patient
- Parents refuse to sign informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Quadruple blind
- Primary purpose
- Supportive care
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07200063 · AgNP vs CHX Mouthwashes