Comparison Of Keratometric Readings Pre and Post Pterygium Excision With Conjunctival Autograft Transplantation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Pterygium Excision with Conjunctival Autograft.
- Who it may be relevant to
- Registry conditions: Pterygium, Corneal Astigmatism. Basic parameters: 30 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Pakistan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Pterygium, often called "surfer's eye," is a common eye condition in which a raised, fleshy growth of tissue extends from the white part of the eye onto the clear cornea. This growth can cause redness, irritation, blurred vision, and, in advanced cases, changes in the curvature of the cornea leading to distorted vision (astigmatism). The condition is more frequent in people exposed to sunlight, dust, and dry environments. The standard treatment for symptomatic pterygium is surgical removal. However, simple removal has a high chance of recurrence. To reduce this risk, surgeons commonly use a technique called conjunctival autograft transplantation, where a small piece of the patient's own conjunctiva is placed over the area after excision. This method not only lowers the recurrence rate but may also improve vision by reducing corneal irregularities. This study is designed to measure the changes in corneal curvature (keratometric readings) before and after pterygium excision with conjunctival autograft transplantation. By comparing preoperative and postoperative measurements, the study aims to determine how much this surgery improves corneal shape and reduces astigmatism. The hypothesis is that pterygium excision with conjunctival autograft transplantation will lead to a significant improvement in keratometric readings and reduce irregular astigmatism, thereby improving visual quality. This research will provide local evidence of the effectiveness of this procedure and help guide treatment strategies for patients suffering from pterygium-related visual problems.
Interventions
- Procedure Pterygium Excision with Conjunctival Autograft
Excision of primary Grade II or Grade III pterygium Conjunctival autograft harvested and transplanted at the excision site Graft secured with sutures
Primary outcome measures
- Change in Keratometric Readings (K1 and K2) [Time frame: Baseline (pre-operative) and 1 month post-operative.]
Secondary outcome measures (1)
- Change in Astigmatism [Time frame: Baseline (pre-operative) and 1 month post-operative.]
Eligibility criteria
Inclusion criteria
- Adults of either sex aged >30 to 70 years.
- Phakic eyes.
- Primary pterygium, Grade II or Grade III (as per protocol grading).
- Presence of corneal astigmatism on pre-operative assessment.
- Scheduled for pterygium excision with conjunctival autograft transplantation at the study site.
- Able to provide written informed consent and to attend the 1-month postoperative assessment.
Exclusion criteria
- Pseudophakic or aphakic eyes.
- Recurrent pterygium.
- Prior keratoplasty or trabeculectomy in the study eye.
- Keratoconus or other corneal pathologies that can independently induce astigmatism.
- Lenticular astigmatism or significant lens pathology affecting refraction.
- Eyes planned for simple pterygium excision without conjunctival autograft.
- Any ocular condition or systemic illness judged likely to interfere with keratometric or refractive measurements, follow-up, or surgical safety.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Pakistan · 1 center
- Mughal Eye Hospital Trust — Lahore
Identifiers
NCT: NCT07198126 · MughalETH1