Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Phenotypes of ICU delirium.
- Who it may be relevant to
- Registry conditions: Delirium, Post ICU Syndrome. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Clinical Phenotypes of ICU Delirium and Subsequent Impairment of Physical, Cognitive and Mental Health During Transition From ICU to Hospital Wards
Overview
The goal of this observational study is to learn about the disability profile during transition from ICU to hospital wards of delirium patients, including cognitive impairment, physical dysfunction and psychological disorders. The main question it aims to answer is: * What is the main rehabilitation problem during transition from ICU to hospital wards for patients who experienced ICU delirium? * Dose different phenotypes of ICU delirium shows different rehabilitation problem during ICU transition? Participants will be followed up and assessed by questionnaires after discharge from ICU to hospital wards until hospital discharge.
Interventions
- Other Phenotypes of ICU delirium
The included delirium patients will be divided into different phenotypes, according to delirium risk factors such as age, history of cerebrovascular accident, blood transfusion, surgery duration etc.
Primary outcome measures
- Physical impairment [Time frame: At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge]
- Cognitive impairment [Time frame: At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge]
- Mental health [Time frame: At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge]
Secondary outcome measures (2)
- Hospital stay [Time frame: up to 30 days]
- In-hospital Mortality [Time frame: up to 30 days]
Eligibility criteria
Inclusion criteria
- patients aged above 18-year-old
- at least one positive screening of CAM-ICU (Confusion Assessment Method for ICU) assessment during ICU stay
- patients are transferred to hospital ward after ICU discharge
Exclusion criteria
- patients are with severe dementia
- blindness, deafness or inability to understand mandarin
- life expectancy of less than 24h
- stayed in ICU more than one-month after the first CAM-ICU positive screening
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Zhongshan Hospital, Fudan University — Shanghai
Identifiers
NCT: NCT07193797 · NSFC-7220040527