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Recruiting NCT07191951

Shanghai Clinical Cohort - Adrenal Disease

Observational Adrenal Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification..
Who it may be relevant to
Registry conditions: Adrenal Disease. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

As a vital organ responsible for producing life-sustaining hormones, the adrenal gland is associated with a wide range of diseases. These diseases affect multiple systems throughout the body and carry a high rate of mortality and disability. Current diagnosis and treatment face several challenges: significant variability in hormone testing results, inaccurate localization via imaging techniques, unclear molecular characteristics of adrenal tumors, and difficulty in determining prognosis through pathology. Therefore, establishing a clinical research cohort for adrenal diseases is essential. Such a cohort will enable in-depth exploration of disease mechanisms, identification of disease subtypes, optimization of diagnostic criteria, evaluation of treatment efficacy, advancement of personalized medicine, and formulation of prevention and treatment strategies.

Interventions

  • Other Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.
    Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.

Primary outcome measures

  • Post-Treatment Remission Rate [Time frame: at least six months or more]
  • Treatment Response Rate [Time frame: at least six months or more]

Eligibility criteria

Inclusion criteria

  • A signed and dated informed consent form
  • Commitment to abide by the study procedures and cooperate with the implementation of the entire study process
  • Patients diagnosed with adrenal diseases, including aldosteronism, Cushing's syndrome, pheochromocytoma, adrenocortical carcinoma, and congenital adrenal hyperplasia; regardless of whether they have received adrenal surgery, radiotherapy, and/or medication therapy
  • Aged between 18 and 75 years

Exclusion criteria

  • Subjects meeting any of the following criteria will be excluded from this study:
  • Refuse to sign the informed consent form
  • Patients without adrenal diseases
  • Have specified diseases or conditions (physical or psychological, identified through physical examination) that warrant exclusion from the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Jiang yiran — Shanghai

Identifiers

NCT: NCT07191951 · SHDC2025CCS022

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗