Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Ginger, Placebo.
- Who it may be relevant to
- Registry conditions: Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Tunisia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Preoperative Ginger for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Double-Blind Randomized Controlled Trial
Overview
This study aims to evaluate whether preoperative oral administration of ginger (800 mg, given 2 hours before surgery) reduces the incidence and severity of postoperative nausea and vomiting (PONV) within the first 24 hours after laparoscopic cholecystectomy.
Interventions
- Drug Ginger
Patients will receive 800 mg of oral ginger 2 hours before laparoscopic cholecystectomy - Drug Placebo
Patients will receive an oral placebo capsule identical in appearance to ginger, administered 2 hours before laparoscopic cholecystectomy
Primary outcome measures
- Incidence of postoperative nausea and vomiting (PONV) within 2 hours post-surgery [Time frame: 2 hours after surgery.]
Secondary outcome measures (5)
- Recurrence of PONV beyond 2 hours postoperatively [Time frame: From 2 hours to 24 hours after surgery.]
- Incidence of postoperative nausea and vomiting (PONV) within 24 hours post-surgery [Time frame: 24 hours after surgery.]
- Total number of vomiting episodes [Time frame: Within 24 hours post-surgery.]
- Use of rescue antiemetics [Time frame: 24 hours postoperatively]
- Incidence of ginger-related adverse events [Time frame: Within 24 hours after surgery]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years.
- Scheduled for elective laparoscopic cholecystectomy under general anesthesia.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Able to understand the study procedures and provide written informed consent.
Exclusion criteria
- Known allergy or hypersensitivity to ginger
- Documented history of bleeding disorders or current treatment with anticoagulant agents
- History of severe postoperative nausea and vomiting or an Apfel score of 4
- Administration of antiemetic drugs or corticosteroids during the preoperative period
- Pregnancy or breastfeeding
- Active gastrointestinal or liver disease
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Tunisia · 1 center
- Mohamed Taher Maamouri University Hospital — Nabeul
Identifiers
NCT: NCT07190495 · GINGER PONV