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Recruiting NCT07189507

Suitability of the 26 °C Indoor Temperature Upper Limit for Older Adults: Impacts of Clothing and Daily Activity

No phase Interventional Heat Stress Physiological Stress

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Simulated indoor temperature upper limit.
Who it may be relevant to
Registry conditions: Heat Stress, Physiological Stress. Basic parameters: 65 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Canada
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of the 26 °C Indoor Temperature Upper Limit Considering Clothing Insulation and Daily Activity in Older Adults

Overview

While an upper limit of 26°C has been shown to be protective for heat-vulnerable older occupants (DOI: 10.1289/EHP11651), this recommendation did not consider the added heat burden associated with increases in internal heat production accompanying activities of daily living or the restriction to heat loss caused by clothing insulation. To safeguard the health of older adults, health agencies worldwide recommend the remain in cool space indoors, avoid strenuous activity, wear lightweight clothing, and drink cool water regularly throughout the day. However, older adults do not sense heat as well as their younger counterparts. Consequently, they may not take appropriate countermeasures to mitigate physiological strain from indoor overheating. This may include overdressing despite high indoor temperatures. In other cases, individuals may wear insulated clothing in hot weather to observe cultural or religious modesty requirements, which serve as expressions of faith and identity rather than a tool for thermoregulation. Further, individuals may be unaware of the consequences of increases in physical activity on heat gain and may therefore not adjust their normal day-to-day activity levels to prevent potentially dangerous rises in body temperature. Consequently, this may necessitate a lowering of recommended upper indoor temperature limit during hot weather. To address these important considerations, on separate occasions the investigators will assess the change in body temperature and cardiovascular strain in older adults (65-85 years) exposed for 8 hours to the recommended indoor temperature upper limit of 26°C and 45% relative humidity equivalent humidex of 29 (considered comfortable) while they A) perform seated rest dressed in light clothing (t-shirt, shorts and socks), B) perform light exercise (stepping exercise to simulate activities of daily living, 4-4.5 METS) every hour (except during lunch hour period) dressed in light clothing, C) perform light exercise (4-4.5 METS) every hour (except during lunch hour period) dressed in light clothing (t-shirt, shorts and socks) and an added clothing layer (sweatshirt and sweatpants) and D) perform seated rest dressed in light clothing (t-shirt, shorts and socks) and an added clothing layer (sweatshirt and sweatpants). With this experimental design, investigators will assess the effects of added clothing insulation and light activity, representative in activities of daily living on physiological strain and identify whether refinements in the recommended 26°C indoor temperature limit may be required.

Interventions

  • Other Simulated indoor temperature upper limit
    Older adults exposed to an 8-hour simulated exposure.

Primary outcome measures

  • Core temperature (Peak) during daylong exposure to indoor temperature limit. [Time frame: End of 8 hour daylong exposure]
Secondary outcome measures (12)
  • Profiles of Mood States (POMS) during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Environmental Symptoms Questionnaire (ESQ) during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Activity levels during daylong exposure to indoor overheating [Time frame: End of 8 hour daylong exposure]
  • Hydration status during daylong exposure to indoor overheating [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Perceived exertion scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Feel good scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Orthostatic intolerance symptoms assessment during daylong exposure to indoor temperature limit. [Time frame: At end of 8 hour daylong exposure.]
  • Thermal sensation 2 scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Thermal sensation scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Arousal scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Thirst sensation scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]
  • Thermal comfort scale during daylong exposure to indoor temperature limit. [Time frame: At the start (hour 0) and end of 8 hour daylong exposure]

Eligibility criteria

Inclusion criteria

  • Non-smoking.
  • English or French speaking.
  • Ability to provide informed consent.
  • with or without a) chronic hypertension (elevated resting blood pressure; as defined by Heart and Stroke Canada and Hypertension Canada), b) type 2 diabetes as defined by Diabetes Canada, with at least 5 years having elapsed since time of diagnosis

Exclusion criteria

  • Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness).
  • Serious complications related to your diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy).
  • Uncontrolled hypertension - BP >150 mmHg systolic or >95 mmHg diastolic in a sitting position.
  • Restrictions in physical activity due to disease (e.g. intermittent claudication, renal impairment, active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis, etc.).
  • Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable.
  • Cardiac abnormalities identified during screening

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Single blind
Primary purpose
Basic science

Study locations

Canada · 1 center
  • University of Ottawa — Ottawa

Identifiers

NCT: NCT07189507 · HEPRU-2025-09-A

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗