Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Primary Aldosteronism, Adrenal Tumor, Cushing s Syndrome, Pheochromocytoma/Paraganglioma (PPGL). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Dynamic Monitoring and Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
Overview
The main goal of this study is to follow patients with functional adrenal tumors during the time before and after their surgery. The main questions it aims to answer are: * What heart and blood pressure changes do patients with different types of adrenal tumors have before surgery? * What factors affect how the heart and blood pressure recover after surgery? * Do the heart and blood pressure conditions before surgery influence recovery and the risk of heart or brain problems after surgery? Patients will have heart ultrasound checks and health monitoring before and after surgery. The results will help doctors choose the right medicines before surgery, better understand possible risks during the operation, and make safer treatment plans for patients with functional adrenal tumors.
Primary outcome measures
- Recovery of cardiac function after adrenal surgery [Time frame: from enrollment to 4,24,48 weeks after surgery]
Secondary outcome measures (1)
- Recovery of blood pressure after adrenal surgery [Time frame: from enrollment to 4,24,48 weeks after surgery]
Eligibility criteria
Inclusion criteria
- Patients diagnosed in the Department of Urology, Peking University First Hospital with pheochromocytoma and paraganglioma (PPGL), primary aldosteronism (PA), or Cushing syndrome (CS);
- Written informed consent obtained.
Exclusion criteria
- Patients with PPGL, PA, or CS who receive medication or conservative treatment and are not eligible for surgical resection;
- Patients with communication disorders or severe physical impairments such as aphasia, or visual/hearing disabilities;
- Patients with severe mental illness who cannot cooperate with the study;
- Pregnant women or patients otherwise deemed unsuitable for participation by the investigators.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Peking University First Hospital — Beijing
Identifiers
NCT: NCT07182175 · 2024yan411-002