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Recruiting NCT07179055

An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

Phase II Interventional Dry Eye

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: VSJ-110, Placebo.
Who it may be relevant to
Registry conditions: Dry Eye. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

An Eight-Week, Double-Masked, Randomized, Placebo-Controlled, Phase 2, Evaluation of the Safety and Efficacy of VSJ-110 Ophthalmic Solution in the Treatment of Dry Eye

Overview

The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye.

Interventions

  • Drug VSJ-110
    ophthalmic solution
  • Drug Placebo
    ophthalmic solution

Primary outcome measures

  • Corneal Staining [Time frame: Measured over an 8-week treatment period]
Secondary outcome measures (2)
  • Schirmer's Tear Test [Time frame: Measured over an 8-week treatment period]
  • Eye Dryness Score (EDS) of the Visual Analogue Scale (VAS) [Time frame: Measured over an 8-week treatment period]

Eligibility criteria

Inclusion criteria

  • Be at least 18 years of age of either gender and any race.
  • Provide written informed consent and sign the HIPAA form.
  • Be willing and able to follow all instructions and attend all study visits.

Exclusion criteria

  • Use of any of the disallowed medications during the washout and study period.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

United States · 5 centers
  • Vanda Investigational Site — Newport Beach
  • Vanda Investigational Site — Andover
  • Vanda Investigational Site — Shelby
  • Vanda Investigational Site — Memphis
  • Vanda Investigational Site — Lynchburg

Identifiers

NCT: NCT07179055 · VP-VSJ-110-2202

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗