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Enrolling by invitation NCT07177378

Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap Closure

No phase Interventional Osteomyelitis of Jaw

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: management of medication related osteonecrosis of the jaw.
Who it may be relevant to
Registry conditions: Osteomyelitis of Jaw. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Management of Medication Related Osteonecrosis of the Jaws Using Piezosurgery With Simultaneous Double Periosteal Flap Closure

Overview

20 patients with MRONJ underwent surgical debridement using piezosurgery then closure using double periosteal flap

Detailed description

20 patients with MRONJ underwent surgical debridement, crestal incision and oblique releasing incision were performed to expose the area of osteomyelitis, then squesterum was removed using piezosurgery. After complete debridement, the periosteal layer was dissected from mucoperiosteal buccal flap and based superiorly, then turn upward to be sutured to the lingual flap followed by suturing of buccal flap to achieve double layers closure

Interventions

  • Device management of medication related osteonecrosis of the jaw
    after buccal flap reflection, the bone osteonecrosis was debrided using piezosurgery. the buccal mucoperiosteal flap was dissected to two layers first, the periosteal layer was based superiorly and the mucosal flap to achieve double layers closure.

Primary outcome measures

  • evaluation of pain [Time frame: one month]
  • wound healing [Time frame: one -3 months]

Eligibility criteria

Inclusion criteria

  • patients with MRONJ

Exclusion criteria

  • Patients had a history of radiotherapy
  • Patients need only conservative treatment

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Faculty of Dentistry, Tanta University — Tanta

Identifiers

NCT: NCT07177378 · 1981

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗