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Not yet recruiting NCT07171541

Correlation Between OCT and Mf-ERG Findings With BCVA in Patients With Macular Dystrophy

Observational Macular Dystrophy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: OCT ,mFERG,VA test.
Who it may be relevant to
Registry conditions: Macular Dystrophy. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity in Patients With Macular Dystrophy

Overview

Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity in patients with macular dystrophy.

Detailed description

Macular dystrophies cause progressive central vision loss, but the relationship between structural retinal changes (OCT) and functional deficits (mf-ERG) with visual outcomes remains poorly understood. Current clinical assessment relies primarily on visual acuity, which inadequately reflects retinal damage or predicts disease progression. This knowledge gap limits prognostic accuracy and optimal patient management. Recent advances in OCT and mf-ERG technology provide an opportunity to establish robust structure-function correlations. Understanding these relationships will enhance patient care through improved prognosis, standardized monitoring protocols, and better clinical trial outcome measures for macular dystrophy patients.

Interventions

  • Diagnostic test OCT ,mFERG,VA test
    retinal photography by OCT, VA measurement, and mfERG test

Primary outcome measures

  • BCVA (best corrected visual acuity) [Time frame: Day 1/month 3]
  • CMT (central macular thickness) μm Central macular thickness measurement using optical coherence tomography [Time frame: Day1/month 3]
  • mf-ERG amplituide nV/deg2 [Time frame: Day 1/month 6]

Eligibility criteria

Inclusion criteria

  • All patients diagnosed with macular dystrophy in Tiba Eye Centre, Egypt, Assiut, during the period of the study

Exclusion criteria

  • The patients diagnosed with macular dystrophy refuse to contribute to the study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-only

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07171541 · CBOTMEFVAPMD

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗