The Effect of Preoperative Gabapentin on Postoperative Pain Control and Analgesic Requirements Following Bariatric Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Group 1, Group 2.
- Who it may be relevant to
- Registry conditions: Bariatric Surgery Analgesia. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The importance of bariatric anesthesia and analgesia research cannot be ignored as it can inform and improve the perioperative protocols for other patients with morbid obesity irrespective of the surgical procedures they are undergoing
Detailed description
Among various postoperative complications, pain is the main adverse event experienced by patients. Good control of postoperative pain is an important factor for reducing early postoperative complications such as pulmonary embolism, deep vein thrombosis, ileus, and respiratory infections, and for decreasing length of stay, lowering costs, and increasing patient satisfaction
Interventions
- Drug Group 1
Will receive a single dose of gabapentin 300 mg preoperatively before standard general anesthesia - Drug Group 2
will receive a placebo before standard general anesthesia
Primary outcome measures
- Comparing pain score between the two groups during 1st postoperative 24 hours using visual analogue score (VAS [Time frame: 24 hours postoperative]
Eligibility criteria
Inclusion criteria
- patients with American Society of Anesthesiologists physical status ASA I to III
- both genders
- Morbid obese scheduled for bariatric surgery
Exclusion criteria
- patients with impaired liver or kidney disease
- patients with history of hypersensitivity to gabapentin
- patients with history of alcohol abuse, chronic pain or frequent use of analgesic
- patients with uncontrolled medical disease
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Prevention
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07169006 · MD326/2024