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Not yet recruiting NCT07161817

Effect of Postural Changes on Postoperative Hypoxemia

No phase Interventional Postoperative Hypoxemia Position Differences

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Lateral positioning, Semirecumbent positioning.
Who it may be relevant to
Registry conditions: Postoperative Hypoxemia, Position Differences. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effect of Semirecumbent and Lateral Positioning on Postoperative Hypoxemia : a Randomized Controlled Trial

Overview

The goal of this clinical trial is to learn which positioning strategy works better to prevent postoperative hypoxemia in surgical patients: semirecumbent positioning or lateral positioning. It will also learn about the safety and effectiveness of these two positioning approaches. The main questions it aims to answer are: Does semirecumbent positioning reduce the incidence of postoperative hypoxemia more effectively than lateral positioning? Does lateral positioning reduce the incidence of postoperative hypoxemia more effectively than semirecumbent positioning? What are the differences in patient comfort and recovery outcomes between these two positioning strategies? Researchers will compare semirecumbent positioning directly to lateral positioning to see which approach is more effective in preventing postoperative hypoxemia. Participants will: Be randomly assigned to either semirecumbent positioning or lateral positioning after surgery Have their oxygen levels and breathing monitored regularly during the postoperative period Receive standard post-surgical care with their assigned positioning strategy Be assessed for comfort levels and any positioning-related complications Have their recovery progress tracked throughout their hospital stay.

Interventions

  • Behavioral Lateral positioning
    Patients allocated to lateral positioning were placed at 90° on a horizontal bed, supported with a pillow to maintain neutral alignment of the spine and avoid hyperextension or forward flexion of the neck. No preference was specified for left or right lateral decubitus positioning, allowing flexibility based on patient comfort and surgical requirements.
  • Behavioral Semirecumbent positioning
    Patients in the semi-recumbent position were placed in the bed and the head of the bed was raised by 30 °, allowing flexibility based on patient comfort and surgical requirements.

Primary outcome measures

  • Incidence of hypoxaemia [Time frame: Within 24 hours after the surgery was completed]
Secondary outcome measures (6)
  • Rrequency of airway rescue interventions [Time frame: Within 24 hours after the surgery was completed]
  • incidence of severe hypoxaemia [Time frame: Within 24 hours after the surgery was completed]
  • Lowest oxygen saturation [Time frame: Within 24 hours after the surgery was completed]
  • Duration of stay in the post-anaesthesia care [Time frame: Perioperative/Periprocedural]
  • wound pain [Time frame: Perioperative/Periprocedural]
  • Adverse events [Time frame: Perioperative/Periprocedural]

Eligibility criteria

Inclusion criteria

  • Patients aged 18 or above and 80 or below who received general anesthesia and intubation

Exclusion criteria

Inclusion criteria

\- Patients aged 18 years and above, and 80 years and below, who received general anesthesia and intubation;

Exclusion criteria

  • Presence of hypotension or bradycardia upon entering the anesthesia recovery room;
  • Preoperative hypoxemia;
  • Surgical procedures where body position adjustment is not possible or is prohibited due to the nature of the surgery;
  • Surgical procedures involving severe cardiovascular or cerebrovascular diseases, severe pulmonary diseases, intracranial hypertension, etc.;
  • Intubation more than 3 times.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Publications

  • Wang X, Guo K, Sun J, Yang Y, Wu Y, Tang X, Xu Y, Chen Q, Zeng S, Wang L, Liu S. Semirecumbent Positioning During Anesthesia Recovery and Postoperative Hypoxemia: A Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2416797. doi: 10.1001/jamanetworkopen.2024.16797. PMID 38941098
  • Ye H, Chu LH, Xie GH, Hua YJ, Lou Y, Wang QH, Xu ZX, Tang MY, Wang BD, Hu HY, Ying J, Yu T, Wang HY, Wang Y, Ye ZJ, Bao XF, Wang MC, Chen LY, Wang XX, Zhang XB, Huang CS, Wang J, Lu YP, Luo FQ, Zhou W, Wang CG, Cheng H, Liu WJ, Luo J, Wu YQ, Li RR, Wang D, Hou LQ, Shi L, Zhang J, Wang K, Pi X, Zhou R, Yang QQ, Wan PL, Li H, Wu SJ, Song SW, Cui P, Shu L, Islam N, Fang XM. Effect of lateral versus s PMID 40829895

Identifiers

NCT: NCT07161817 · Postoperative Hypoxemia

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗