Sex-Based Differences of LA: Impact on AF Ablation.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Atrial fibrillation ablation.
- Who it may be relevant to
- Registry conditions: Atrial Fibrillation (AF). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Spain
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Sex-Based Differences of Left Atrium: Impact on Atrial Fibrillation Ablation.
Overview
The aim of the study is to assess sex-related differences in patients who underwent a first ablation procedure for paroxysmal or persistent AF, guided by the personalized ablation strategy of the BY-LAWT protocol. Specifically, to compare anatomical characteristics, procedural parameters, and clinical outcomes between sexes.
Interventions
- Procedure Atrial fibrillation ablation
Atrial fibrillation ablation with RF, guided by navigation system
Primary outcome measures
- Efficacy in AF freedom [Time frame: from the procedure to 12 months later]
Eligibility criteria
Inclusion criteria
- Patients who underwent a first ablation procedure for atrial fibrillation (paroxysmal or persistent).
- Availability of an adequate pre-procedural cardiac CT scan for LAWT, LAV and inFAT analysis.
- Availability of complete procedural data, including ablation index (AI) values recorded using the SmartTouch catheter (Biosense Webster).
- Availability of 12-month follow-up data for efficacy and safety endpoint evaluation.
- Ablation performed according to the by-LAWT protocol
Exclusion criteria
- Age < 18 years.
- Previous cardiac ablation (including AF ablation or other arrhythmias).
- Incomplete data regarding procedural parameters, or follow-up.
- Poor quality pre-procedural cardiac MDCT
- Ablation not performed according to the BY-LAWT protocol.
- Structural heart disease (e.g., dilated cardiomyopathy, valvular heart disease with surgical indication) that could substantially influence atrial dimensions or ablation response.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Spain · 1 center
- Teknon Medical center — Barcelona
Identifiers
NCT: NCT07159685 · Sex-Tailored By-LAWT AF