Proprioceptive Error Correction for Post-Stroke Upper Limb Rehabilitation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Electrical stimulation cue, Visual stimulation cue, No cue.
- Who it may be relevant to
- Registry conditions: Ischemic Stroke, Proprioception. Basic parameters: from 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Proprioceptive Error Correction Technique Development to Promote Post-stroke Upper Limbs Motor Rehabilitation
Overview
The investigators aim to develop sensory transformation and augmentation technologies that minimize the impact of proprioceptive errors, thereby significantly enhancing motor learning and rehabilitation of the upper limbs. This study is designed to test proprioceptive error compensation techniques in stroke patients. The human nervous system often receives mismatched information from vision and proprioception during upper limb control, resulting in conflicting sensory inputs that limit the effectiveness of motor learning. In other words, real-time sensory feedback - a critical component of motor learning in the nervous system - is not reliably delivered. Therefore, this study seeks to resolve sensory conflicts by providing additional sensory information through electrical stimulation, with the goal of dramatically improving the effectiveness of motor learning.
Interventions
- Behavioral Electrical stimulation cue
A single 30-minute session is provided. Electrodes are attached to the cubital fossa, and stimulation is delivered at a frequency that increases up to 70 Hz as the elbow joint approaches the target angle. Target angles are set between 0 degrees and 120 degrees, based on each participant's available range of motion determined during the initial assessment. Participants adjust their elbow joint angle to match the provided target angle using feedback from the electrical stimulation. When the elbow - Behavioral Visual stimulation cue
A single 30-minute session is provided. The difference between the current elbow joint angle and the pre-set target angle is displayed on a screen using two colored needles (a red needle for the target angle and a black needle for the current elbow joint angle). The target angle is set within each participant's available range of motion based on the initial assessment. Participants continue the intervention by adjusting their elbow angle using the visual feedback. When the elbow joint angle matc - Behavioral No cue
A single 30-minute session is provided. The target angle is determined within each participant's available range of motion based on the initial assessment. Throughout the session, participants receive verbal feedback from the assessor and adjust their elbow joint angle accordingly to match the target angle.
Primary outcome measures
- Improvement in upper limb motor function [Time frame: 6 visits over 3 weeks]
Secondary outcome measures (1)
- Proprioceptive accuracy [Time frame: Baseline before intervention and immediately after the 30-minute training session]
Eligibility criteria
Inclusion criteria
- Diagnosed with ischemic or hemorrhagic stroke
- Stroke confirmed by CT or MRI
- Stroke patients with proprioceptive sensory deficits
- Chronic stroke patients with onset at least 3 months prior
- Able to voluntarily flex and extend the elbow joint
- Age 19 years or older
- Provide written informed consent (participant or legal representative)
Exclusion criteria
- Severe pain during elbow joint movement
- Elbow joint contracture, spasticity, ataxia, musculoskeletal disorders, fractures, - non-healing ulcers, or open wounds
- Progressive or unstable stroke
- Presence of unilateral neglect
- Coexisting severe neurological disorders
- Major psychiatric disorders such as major depressive disorder, schizophrenia, bipolar disorder, or dementia Presence of a pacemaker
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
South Korea · 1 center
- Shinchon Severance Rehabilitation Hospital — Seoul
Identifiers
NCT: NCT07156955 · 2025-06-075-001