Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Red light exposure, Red-blue light exposure.
- Who it may be relevant to
- Registry conditions: Perianal Abscess. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Abscess: a Single-center Prospective Open-label Randomized Clinical Trial
Overview
This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery. A total of 222 eligible patients were randomly allocated equally into three groups (74 per group):①Routine Care Group: Standard wound care including cleansing and dressing changes；②Red Light Therapy Group: Routine care plus red light phototherapy；③Combined Red-Blue Light Therapy Group: Routine care plus concurrent red and blue light phototherapy.Wound healing time and incidence of complications were compared to assess postoperative recovery across interventions. The primary hypothesis posits that adjunctive phototherapy-particularly combined red-blue light irradiation-will significantly enhance wound healing, reduce edema and pain, and decrease complication rates (e.g.bleeding, urinary retention) compared to routine care alone.
Interventions
- Device Red light exposure
Patients in the red light group received red light therapy concurrently with standard care. - Device Red-blue light exposure
Patients in the red and blue light group received combined red and blue light therapy concurrently with standard care。
Primary outcome measures
- Wound healing time [Time frame: Measurements were taken over a time frame of 24 hours postoperatively to complete epithelialisation.]
Secondary outcome measures (5)
- Postoperative pain intensity [Time frame: Baseline, Day 1, 3, 5, 7, and Day 14±2]
- Peripheral tissue edema（Grade 0-3） [Time frame: Day 1, 3, 5, 7, and Day 14±2]
- Assessment of Granulation Tissue in Wound Bed [Time frame: Day 1, 3, 5, 7, and Day 14±2]
- Length of hospital stay [Time frame: From surgery end to discharge (up to 7 days)]
- Complication incidence [Time frame: Within 30 days postoperatively]
Eligibility criteria
Inclusion criteria
- Aged between 18 and 75 years;
- Clinical diagnosis of perianal abscess；
- Procedure: Radical resection with incision and drainage.
Exclusion criteria
- Concurrent anorectal disorders (hemorrhoids, anal fissure) or malignancies/infectious diseases；
- History of psychiatric disorders；
- Analgesic use within 7 days preoperatively；
- Coagulopathy or cardiac/hepatic dysfunction；
- Pregnancy or lactation；
- Contraindications to phototherapy；
- IBD-related perianal abscess.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
China · 1 center
- Affiliated Hospital of Putian University — Putian
Identifiers
NCT: NCT07155356 · AHPutianU-012