Not yet recruiting NCT07154940

Diagnostic Yeild of Esophagogastrodudenoscopy in Pediatric Chronic Abdominal Pain

— Observational Endoscopy in Chronic Abdominal Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied: This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to: Registry conditions: Endoscopy in Chronic Abdominal Pain. Basic parameters: 6 years — 18 years · All.
What needs checking: Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place: Center list to be confirmed — check the primary protocol.
Next step: Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Evaluate the diagnostic yeild of esophagogastrodudenoscopy in children with chronic abdominal pain

Determine the prevalence of endoscopic and histopathological abnormalities in symptomatic children undergoing esophagogastrodudenoscopy for chronic abdominal pain [Time frame: Oct 2025 to april 2027]

Children aged 6 to 18 years presenting with chronic abdominal pain which defined according to the Rome IV criteria as persistent or recurring abdominal pain that has been present for at least 3 months, with symptom onset at least 6 months prior to diagnosis. This pain must be continuous or nearly continuous, and only occasionally related to physiological events like eating or defecation. Furthermore, the pain must limit some aspect of daily functioning, and it is not feigned or explained by another medical condition and referred to GIT unit for Esophagogastroduodenoscopy and not undertreatment based on clinical judgment due to the presence of one or more of the following:

Alarm symptoms (e.g., weight loss, anemia, Hematemesis, Dysphagia, persistent vomiting, nocturnal pain)
Failure of empiric therapy (e.g., proton pump inhibitors or dietary modifications)
Suspicion of an underlying organic disease (e.g., celiac disease or Helicobacter pylori infection)

Acute abdominal pain
Children aged less than 6 years and more than 18 years
Recent use of proton pump inhibitors (within 2 weeks) or antibiotics (within 4 weeks) before endoscopy.
Children meeting the criteria of functional abdominal pain according to Rome IV criteria in which was defined as as recurrent or chronic abdominal pain that is not explained by another medical condition and is not solely associated with physiological events like eating or menstruation. It must occur at least 4 times per month for at least 2 months, and diagnostic evaluation should rule out other conditions .
Children with contraindications to undergoing EGD (e.g., severe respiratory or cardiac conditions).
Children who refuse to participate or whose parents do not provide consent.
Children previously diagnosed with recurrent abdominal pain -

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Center list to be confirmed — check the primary protocol.

NCT: NCT07154940 · AUCH AssiutU