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Recruiting NCT07146659

Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings

Observational Fibroid Uterus Polyp Uterus Retained Products of Conception

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Fibroid Uterus, Polyp Uterus, Retained Products of Conception. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings : A Prospective Observational Study

Overview

This is an observational prospective monocentric study which aims to compare operative hysteroscopies performed in the operating room under general or loco-regional anesthesia and those performed outside the operating room (outpatient operative hysteroscopy). The primary outcome is the success rate of the procedure. Secondary outcomes include postoperative pain, patient satisfaction, complications, and time to return to work.

Detailed description

Operative hysteroscopy is a key technique for the treatment of intrauterine pathologies such as endometrial polyps, submucosal fibroids, retained products of conception. Traditionally, operative hysteroscopies are performed in the operating room under general or regional anesthesia, requiring either ambulatory or inpatient hospitalization.

In recent years, advances in hysteroscopic instrumentation and procedural techniques have made it possible to perform selected operative hysteroscopies in outpatient settings (consultation office) without general or regional anesthesia. Several studies have demonstrated the feasibility, safety, and effectiveness of outpatient operative hysteroscopy, with similar success rates and complication profiles compared to procedures performed in the operating room, although some studies reported higher levels of pain during outpatient procedures (1-3) . Furthermore, cost-effectiveness studies support outpatient procedures by highlighting reduced hospital resource utilization and shorter recovery times for patients (4-6).

The HOPE study aims to evaluate this practice locally at the Centre Hospitalier Intercommunal de Créteil. This prospective monocentric observational study will include approximately 400 patients over a two-year period (July 2025 - May 2027). The primary objective is to compare the success rates of operative hysteroscopies performed in the operating room versus those performed in an outpatient setting. Secondary objectives include assessment of perioperative and postoperative pain, patient satisfaction, complication rates, and the time to return to work.

Data will be collected from medical records and patient-reported outcomes using a satisfaction questionnaire. Inclusion of patients will follow the usual care pathway, without additional interventions or follow-up beyond standard clinical practice.

Primary outcome measures

  • This will be assessed as an ordinal qualitative variable, with procedures classified into three categories:number of complete success, number of partial success, or number of failure. [Time frame: The classification will be determined by the surgeon at the end of the procedure and documented in the operative report (baseline)]
Secondary outcome measures (4)
  • Perioperative and postoperative pain Assessed using the Visual Analogue Scale (VAS) [Time frame: During the procedure (if the patient is awake), immediately after the procedure, and at hospital discharge (baseline)]
  • Patient satisfaction Assessed using a locally developed patient satisfaction questionnaire [Time frame: At hospital discharge.(assessed up to 5 days)]
  • Complications including uterine perforation, hemorrhage, and postoperative infection [Time frame: Recorded during the procedure and immediately afterward (documented in the operative report and medical records), and up to 8 weeks postoperatively during the follow-up consultation if necessary.]
  • 4. Time to return to work Measured as the number of days of sick leave prescribed and actually taken. [Time frame: Up to 8 weeks postoperatively.]

Eligibility criteria

Inclusion criteria

  • Women aged ≥ 18 years

-⁃ Undergoing operative hysteroscopy for intrauterine pathology

  • Able to provid e informed non-opposition
  • French-speaking

Exclusion criteria

  • Patients with contraindications to hysteroscopy
  • Pregnancy
  • Inability to complete follow-up

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

France · 1 center
  • CHI Créteil - Gynécologie et obstétrique — Créteil

Identifiers

NCT: NCT07146659 · HOPE

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗