A National Multicenter Survey on Small Vulnerable Newborns
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Preterm, Small Gestational Age (SGA). Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
A National Multicenter Epidemiological Investigation of Small Vulnerable Newborns in China
Overview
The goal of this nationwide multicenter observational study is to comprehensively investigate the severity of Small Vulnerable Newborns (SVN) issues across China and to propose further preventive and intervention measures. The primary aim is to provide a thorough description of SVN problems using a unified definition and framework, and to develop targeted prevention strategies. Participating centers across the country will collect clinical data on vulnerable newborns under their care and complete detailed questionnaires to support this research.
Primary outcome measures
- Number of small vulnerable newborns [Time frame: From date of hospital admission until the date of discharge or date of death from any cause, whichever came first, assessed up to 1 year.]
- Mortality rate [Time frame: From date of hospital admission until the date of discharge or date of death from any cause, whichever came first, assessed up to 1 year.]
Secondary outcome measures (1)
- Incidence of complications in small vulnerable newborns [Time frame: From date of hospital admission until the date of discharge or date of death from any cause, whichever came first, assessed up to 1 year.]
Eligibility criteria
Inclusion criteria
- Newborns diagnosed as vulnerable infants at the participating hospitals between January 1 and December 31, 2024;
- Meeting any one of the following criteria:
- Diagnosed as small for gestational age (SGA): birth weight below the 10th percentile for infants of the same gestational age and sex;
- Preterm infants: gestational age less than 37 weeks;
- Low Birth Weight (LBW) infants: birth weight less than 2,500 grams.
Exclusion criteria
- Incomplete medical records due to missing data preventing comprehensive case evaluation.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Case-only
Study locations
China · 1 center
- Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine — Shanghai
Identifiers
NCT: NCT07143825 · XH-25-006