Pleural Tissue Culture Versus Pleural Fluid Culture in Infected Effusion
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: pleural biopsy.
- Who it may be relevant to
- Registry conditions: Pleural Tissue Culture. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Microbiological Value of Sonographic Guided Pleural Tissue Culture Plus Pleural Fluid Culture in Patients With Infected Pleural Fluid
Overview
comparison between the result of fluid culture and that of pleural tissue culture
Detailed description
MICROBIOLOGICAL VALUE OF SONOGRAPHIC GUIDED PLEURAL TISSUE CULTURE PLUS PLEURAL FLUID CULTURE IN PATIENTS WITH INFECTED PLEURAL FLUID
Interventions
- Procedure pleural biopsy
To assess whether pleural tissue culture can improve the identification of causative organisms in pleural infections (using the pleural fluid culture), which can aid in selecting appropriate antimicrobial therapy and improve treatment outcomes, thus may provide valuable insights into the utility of pleural tissue culture in managing pleural infection and may guide clinicians in selecting the most appropriate diagnostic approach.
Primary outcome measures
- initial pleural fluid and parietal pleural tissue [Time frame: 2 weeks]
- result of culture [Time frame: one month]
Eligibility criteria
Inclusion criteria
- Exudate neutrophilic pleural fluid aspirate, or met at least one or more of the following criteria: grossly frank purulent, gram stain positive for bacteria, bacterial culture positive, acidic with a pH <7.20, low pleural fluid glucose (<55mg/dL), and CT evidence of pleural infection. Exclusion criteria: Pleural infections by Mycobacterium tuberculosis.Malignant effusion.Coagulation defects.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
Egypt · 1 center
- Chest Department -Faculty of Medicine — Alexandria
Identifiers
NCT: NCT07140003 · pleura,tissue culture,sonograp