Dietary Iron Requirements
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Stable iron isotope.
- Who it may be relevant to
- Registry conditions: Iron Absorption. Basic parameters: 18 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Dietary Iron Requirements in US Adults
Overview
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the iron isotope dilution technique. Following administration and equilibration of a stable iron isotope, participants will be followed for a 12 week study period. Blood will be collected every 4 weeks and the isotopic composition will be determined. Results will help update dietary iron guidelines making sure they better match the specific needs of the US population.
Interventions
- Other Stable iron isotope
Stable iron isotopes will be used to determine iron requirements.
Primary outcome measures
- Iron isotope composition in blood [Time frame: 12 weeks]
Eligibility criteria
Inclusion criteria
- Males and premenopausal females age 18-50 y
- Previously participated in an iron stable isotope study or willing to consume an oral stable iron isotope and undergo a one-year equilibration period
- Willing to refrain from iron-containing supplements for the duration of the study
- Willing to refrain from tobacco smoking for the duration of the study
- Have not donated blood 3 months prior to the start of the study and willing to refrain from donating blood for the duration of the study
- Willing to have blood stored for future use
- Able and willing to comply with study requirements and consent to participate
Exclusion criteria
- Females: pregnant or lactating or plans to become pregnant during the study period
- Inability to provide informed consent and engage in informed consent procedures
- Plans to relocate outside the study area
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Other
Study locations
United States · 2 centers
- LSU Pennington Biomedical Research Center — Baton Rouge
- Cornell University — Ithaca
Identifiers
NCT: NCT07139821 · 2025-036-PBRC