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Not yet recruiting NCT07138534

Investigation of the Effect of Prehabilitation Practice on Patient Outcomes in Frail Patients Planned for Elective Coronary Artery Bypass Graft

No phase Interventional Coronary Artery Bypass Graft (CABG)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: prehabilitation.
Who it may be relevant to
Registry conditions: Coronary Artery Bypass Graft (CABG). Basic parameters: from 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The basic concept of prehabilitation is to increase the functional capacity of the individual to withstand an expected injury. It embodies the idea of being proactive against the common reactive approach of rehabilitation. While the initial prehabilitation model was limited to physical training, it has now evolved into a multimodal entity that includes nutritional optimisation, psychosocial preparation and smoking cessation in addition to exercise programmes. In the last decade, there has been an increasing effort to coincide prehabilitation with surgery, as surgery is rightly perceived as a stressor for human structural and physiological functions.

Detailed description

Frailty is an increasingly recognised risk factor for surgery. The degree of frailty and how this may affect postoperative recovery profiles is unclear. Preoperative frailty may predispose patients to worse outcomes in cardiac surgery; however, there is limited data on how preoperative frailty affects patient outcomes through prehabilitation practices.

Interventions

  • Behavioral prehabilitation
    In addition to exercise programmes, it includes nutritional optimisation, psychosocial preparation and smoking cessation.

Primary outcome measures

  • patients' activities of daily living [Time frame: It will be measured one month after the surgery. The date may vary depending on the patient.]
  • functional capacity [Time frame: It will be evaluated one month after surgery. The date may vary depending on the patient.]
  • Nutritional Status [Time frame: It will be evaluated one month after surgery. The date may vary depending on the patient.]
  • Post-operative recovery status [Time frame: It will be measured one month after the surgery.]

Eligibility criteria

Inclusion criteria

  • frail patient

Exclusion criteria

  • frail patient

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Sequential
Masking
Triple blind
Primary purpose
Supportive care

Study locations

Center list to be confirmed — check the primary protocol.

Publications

  • Steinmetz C, Bjarnason-Wehrens B, Walther T, Schaffland TF, Walther C. Efficacy of Prehabilitation Before Cardiac Surgery: A Systematic Review and Meta-analysis. Am J Phys Med Rehabil. 2023 Apr 1;102(4):323-330. doi: 10.1097/PHM.0000000000002097. Epub 2022 Sep 23. PMID 36149383

Identifiers

NCT: NCT07138534 · 20250715

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗