Recruiting NCT07137286
A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: LDL Hyper-responsiveness. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet
Overview
The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes involved in cholesterol absorption.
Primary outcome measures
- Number of Patients to have a genetic mutation [Time frame: Baseline]
Eligibility criteria
Inclusion criteria
- 18 years of age or older
- LDL-C >170 mg/dL in response to starting a ketogenic diet
Exclusion criteria
- Patients who do not consent to blood draw for genetic testing
- Those with LDL-C <170 mg/dL on a ketogenic diet
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Mayo Clinic — Rochester
Identifiers
NCT: NCT07137286 · 25-002523