Optimizing Dimensions of Reinforcement
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Operant Conditioning Tasks with Reinforcement Manipulations.
- Who it may be relevant to
- Registry conditions: Intellectual Disabilities (F70-F79), Autism. Basic parameters: 6 years — 17 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Optimizing Dimensions of Reinforcement to Enhance Behavioral Interventions
Overview
This study is designed to better understand how certain features of reinforcement affect learning and motivation in individuals with intellectual and developmental disabilities (IDD). Participants will take part in a series of structured teaching sessions that involve simple tasks and reward-based feedback. By changing the timing and amount of rewards, we aim to learn how these factors influence the ability to acquire and maintain new skills. This information may help improve behavioral interventions for individuals with IDD in the future. The study does not involve medications or procedures intended to change participants' health status.
Detailed description
This study examines how key parameters of reinforcement-specifically the timing and amount of rewards-affect learning, motivation, and performance in individuals with intellectual and developmental disabilities (IDD). The experimental design is informed by the Mathematical Principles of Reinforcement (MPR), a quantitative framework for understanding the relationship between reinforcement schedules and behavior.
Participants will complete tabletop tasks in a controlled setting. Tasks are designed to be simple and accessible, such as pressing a button or selecting a picture, and correct responses will earn small rewards. Across sessions, we will systematically vary reinforcement parameters, including inter-reinforcement interval and reinforcer magnitude, to evaluate their effects on response rate, accuracy, and persistence.
This is a Basic Experimental Studies with Humans (BESH) clinical trial, meaning the interventions are intended to understand fundamental behavioral processes, not to produce direct clinical benefit. The data will be analyzed using statistical models derived from MPR to identify which reinforcement dimensions are most effective in maintaining high rates of responding. The results may help refine behavior intervention strategies for individuals with IDD by providing an evidence-based understanding of how to optimize reinforcement delivery.
Interventions
- Behavioral Operant Conditioning Tasks with Reinforcement Manipulations
This behavioral intervention involves structured operant conditioning tasks. Reinforcement parameters (e.g., schedule arrangement, magnitude, and probability) are systematically manipulated to evaluate their effects on behavioral allocation. The primary objective is to assess how variations in reinforcement contingencies influence choice patterns. The procedures are designed to examine fundamental behavioral processes rather than to provide therapeutic benefit.
Primary outcome measures
- Change in rate of behavior across schedules [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
At least 6 years of age
Documented neurodevelopmental condition
Engagement in problem behavior (e.g., aggression, self-injury, property destruction) that can be measured during study sessions
Ability to follow simple instructions
Ability to participate in tabletop choice-based tasks
Availability to complete all scheduled study sessions
Provision of informed consent by participant or legally authorized representative
Exclusion criteria
Severe sensory or motor impairments that would prevent participation in tabletop tasks
Current or recent participation (within the past 30 days) in another interventional behavioral research study that could interfere with study outcomes
Medical or behavioral conditions judged by investigators to pose a safety risk or interfere with data collection
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Basic science
Study locations
United States · 3 centers
- Center for Autism Research, Treatment, and Training — Auburn
- Kennedy Krieger Institute — Baltimore
- Oakland University — Rochester Hills
Identifiers
NCT: NCT07137273 · R21HD113881