Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Behcet Disease, Cranial Nerve Disorder. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features. Cranial nerves control important functions such as vision, facial movement, hearing, swallowing, and balance. The main questions this study will address are: * Do people with BD have changes in cranial nerve function compared to healthy individuals? * Are these changes linked to disease duration, symptoms, or lab results? Participants will: * Answer questions about their medical history and BD symptoms * Complete questionnaires on daily function, mood, and autonomic symptoms * Have a clinical examination of all 12 cranial nerves * Undergo non-invasive electrical tests to assess nerve function This study will not involve any medications. All procedures will be completed in one visit.
Primary outcome measures
- Establish the presence or absence of cranial nerve involvement in BD. [Time frame: Once: Upon patient inclusion]
Secondary outcome measures (1)
- Investigate relation between disease duration (months) and cranial nerve involvement in BD patients [Time frame: Once: Upon patient inclusion]
Eligibility criteria
Inclusion criteria
- Aged 18-75
- Diagnosed with BD according to ACR/EULAR 2013 criteria (patient group)
- Healthy with no relevant medical history (control group)
Exclusion criteria
- Conditions affecting CN assessment (e.g., facial trauma, surgery, radiotherapy)
- Other rheumatologic or autoimmune diseases
- Psychiatric disorders, alcohol/substance abuse
- Pregnant women
- Use of pacemakers or recent botox to masseter muscle
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
Turkey (Türkiye) · 1 center
- Marmara Üniversitesi Tıp Fakültesi — Istanbul
Identifiers
NCT: NCT07135063 · MarmaraU-FTR-RHZ-01