Diaphragm Response in Elderly for Acute Monitoring
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Acute Dyspnea, Acute Respiratory Failure, Diaphragmatic Ultrasound. Basic parameters: from 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Using Diaphragmatic Ultrasound to Predict Acute Respiratory Distress (ARD) in Patients Aged 75 and Over Admitted to the Emergency Department for Acute Dyspnea : Prospective Multicenter Study.
Overview
Acute dyspnea is a common cause of emergency department admissions among elderly patients. Acute respiratory failure is often multifactorial and requires rapid and reliable evaluation. Currently, management relies on clinical, biological, and radiological assessments, but diaphragmatic ultrasound could provide an additional tool for real-time respiratory function evaluation. This study aims to integrate this non-invasive technology into the initial assessment of patients to improve care pathways. Hypothesis : Diaphragmatic ultrasound enables reliable assessment of respiratory function and can predict the need for mechanical ventilation.
Primary outcome measures
- Occurrence of a severe acute respiratory event within 7 days of admission [Time frame: WITHIN 7 DAYS OF ADMISSION]
Secondary outcome measures (2)
- Measurement of diaphragmatic excursion AND Etiology of acute dyspnea [Time frame: within 7 days]
- To evaluate the contribution of diaphragmatic ultrasound to the NEWS2 score performed on admission in predicting the occurrence of acute respiratory distress within 7 days. [Time frame: within 7 days]
Eligibility criteria
Inclusion criteria
- Patients aged ≥ 75 years
- Emergency admission for acute dyspnea
- Requiring an emergency ultrsoung.
Exclusion criteria
- Acute respiratory distress requiring immediate invasive or non-invasive ventilation
- Respiratory rate ≥ 25 breaths/min, and/or SpO2 ≤ 90% on room air, and/or PaO2 ≤ 60 mmHg
- Known diaphragmatic paralysis
- Patients with degenerative neuromuscular disease
- State of shock: systolic blood pressure < 90 mmHg and/or mean arterial pressure < 65 mmHg and/or presence of skin mottling and/or CTR > 3s
- Lactate levels > 2 mmol/L
- Hypercapnic respiratory acidosis (pH < 7.38 and PaCO2 > 45 mmHg)
- Dyspnea due to metabolic acidosis (e.g., diabetic ketoacidosis, renal failure)
- Dyspnea of traumatic origin
- Refusal to participate or inability to provide informed consent
- Patients deprived of liberty
- Patients under guardianship or curatorship
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 9 centers
- Centre Hospitalier Victor Dupouy — Argenteuil
- Centre Hospitalier de Béthune — Béthune
- Centre Hospitalier de Douai — Douai
- Centre Hospitalier Emile Roux — Le Puy-en-Velay
- Centre Hospitalier Sud Ile-de-France — Melun
- Centre Hospitalier de Roubaix — Roubaix
- Centre Hospitalier de Saint-Lô — Saint-Lô
- Centre Hospitalier de Tourcoing — Tourcoing
- … and 1 more center
Identifiers
NCT: NCT07132268 · 2025-01 · ID-RCB