Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic Appendectomy
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In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Metallic clip ligation of the appendicular stump, Suture ligation of appendicular stump.
- Who it may be relevant to
- Registry conditions: Laparoscopic Appendectomy. Basic parameters: 15 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Pakistan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic Appendectomy, a Randomized Control Trial
Overview
Laparoscopic appendectomy is the standard procedure for acute appendicitis. Among the various steps of the procedure one of the rate limiting step is the ligation of the appendicular stump which can be done using suture material, metallic clips and hem o loks. This study compares the effect the using metallic clips versus suture material in the ligation of appendicular stump in terms of length of surgery and associated intra-operative complications. The patients included will be within the age group of 15-60 years, with BMI of 18-28kg/m2, and with acute appendicitis of upto grade 3. The data will be analyzed using SPSS a p value of \<0.05 will be considered as statistically significant.
Interventions
- Device Metallic clip ligation of the appendicular stump
The group A patients will be having the appendicular stump ligated using the metallic clip, and assessed in terms of length of surgery and associated intra operative complications. - Device Suture ligation of appendicular stump
The appendicular stump in the second arm will be ligated using appropriate suture material and assessed in terms of length of surgery and rate of intraoperative complications.
Primary outcome measures
- Length of surgery [Time frame: Intraoperative]
Eligibility criteria
Inclusion criteria
- Both genders, within the age bracket of 15 years - 60 years.
- With a BMI within the range of 18 - 28 kg/m2.
- With a diagnosis made by a consultant surgeon and the grade of appendicitis upto 3.
Exclusion criteria
- Patients with long standing comorbidities including chronic liver disease, diabetes mellitus, chronic kidney disease and hemorrhagic disorders.
- Patients taking anticoagulants, carrier of active cases of Hepatitis B, C and/or HIV.
- Patients on immunosuppression therapy. Diameter of appendicular stump of more than 10mm, perforated appendix, laparoscopic appendectomy converted to open appendectomy pelvic appendicitis and sub-hepatic appendicitis.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Device feasibility
Study locations
Pakistan · 1 center
- Jinnah Hospital Lahore — Lahore
Publications
- Lee JS, Hong TH. Comparison of various methods of mesoappendix dissection in laparoscopic appendectomy. J Laparoendosc Adv Surg Tech A. 2014 Jan;24(1):28-31. doi: 10.1089/lap.2013.0374. Epub 2013 Nov 8. PMID 24206120
- Sohn M, Agha A, Bremer S, Lehmann KS, Bormann M, Hochrein A. Surgical management of acute appendicitis in adults: A review of current techniques. Int J Surg. 2017 Dec;48:232-239. doi: 10.1016/j.ijsu.2017.11.028. Epub 2017 Nov 16. PMID 29155250
Identifiers
NCT: NCT07129746 · Jinnah Hospital Lahore