Correlations of the Microvascular Abnormalities on NVC (Nail Fold Video Capillaroscopy) and GAVE (Gastric Antral Vascular Ectasia) as Seen on EGD
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Video Capillaroscopy.
- Who it may be relevant to
- Registry conditions: Gastric Antral Vascular Ectasia. Basic parameters: 18 years — 95 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The purpose of this research is to determine whether a procedure called capillaroscopy can help distinguish patients who are diagnosed with GAVE (gastric antral vascular ectasia) with an autoimmune disease versus idiopathic/other conditions based on EGD findings.
Detailed description
The primary aim of this study is to define the prevalence and findings (as per quantification) of nail fold video capillaroscopy abnormalities in patients with GAVE. The secondary aim is to compare the findings of NVC and clinical presentation in patients with GAVE.
Interventions
- Device Video Capillaroscopy
A non-invasive imaging technique used to assess capillary structure and morphology in the nailfold area, commonly used in evaluating microvascular changes associated with connective tissue diseases.
Primary outcome measures
- Prevalence and Phenotypic with G.A.V.E [Time frame: From enrollment to end of study once the accrual has been met within baseline of Day 1]
Secondary outcome measures (1)
- Comparing Findings [Time frame: From enrollment to end of study once the accrual has been met within baseline of day 1]
Eligibility criteria
Inclusion criteria
- Patients 18 years and older with gave diagnosis as pair EGD performed in Gastroenterology as standard of care.
Patients with GAVE with connective tissue disease will be compared to patients with GAVE without a connective tissue disease.
Exclusion criteria
- Age less than 18 years of age, pregnant individuals, dialysis dependent, type 2 diabetes, recent hand trauma or manicure (<2 weeks), routine use of vibratory tools, history of acrocyanosis or erythromelalgia, previous diagnosis of a bleeding disorder, diagnosis of psoriasis, diagnosis of anti-phospholipid syndrome, exposure to toluene or benzoyl, diagnosis of psoriasis, diagnosis of COPD.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Non-randomized
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Supportive care
Study locations
United States · 3 centers
- Mayo Clinic (Florida) — Jacksonville
- Mayo Clinic Health System-Eau Claire Clinic — Eau Claire
- Mayo Clinic Health Systems — Eau Claire
Identifiers
NCT: NCT07127952 · 25-001900