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Not yet recruiting NCT07127276

Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of Smartphone Application GERDCare

No phase Interventional GERD (Gastroesophageal Reflux Disease)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Mobile application GERDCare.
Who it may be relevant to
Registry conditions: GERD (Gastroesophageal Reflux Disease). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Vietnam
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare

Overview

Adherence to GERD treatment, including medication, diet, and lifestyle, is essential for symptom control and complication prevention, yet adherence rates remain low due to various demographic and clinical factors. Digital therapeutics, particularly mobile health applications, have shown promising potential in supporting chronic disease management and improving patient outcomes. The GERDCare mobile application was developed with direct input from gastrointestinal experts. It is designed to enhance treatment adherence and patient engagement by offering features such as educational resources, symptom tracking, medication reminders, and direct communication between patients and physicians. We are conducting a single-center, open-label, randomized controlled trial to evaluate the effectiveness of using GERDCare in improving patient adherence. Patients are followed up after four weeks of GERD treatment.

Interventions

  • Other Mobile application GERDCare
    Features of GERDCare that support management of GERD

Primary outcome measures

  • Proportion of patients with good adherence at 4 weeks [Time frame: 4 weeks after recruitment]
Secondary outcome measures (3)
  • Changes in GERD symptom severity [Time frame: 4 weeks after recruitment]
  • Proportion of patients with clinical improvement after 4 weeks [Time frame: 4 weeks after recruitment]
  • Changes of patients' quality of life after 4 weeks [Time frame: 4 weeks after recruitment]

Eligibility criteria

Inclusion criteria

  • ≥18 years old
  • Presents with typical GERD symptoms (regurgitation, heartburn)
  • Owns a smartphone and capable of using smartphone applications.

Exclusion criteria

  • Acute GI conditions (upper GI bleeding, acute peptic ulcer…)
  • GI malignancy (esophageal cancer, gastric cancer…)
  • Severe chronic comorbidities (heart failure, liver failure, chronic kidney disease…)
  • Pregnancy, alcohol abuse, mental health conditions impacting medication adherence or app usage

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

Vietnam · 1 center
  • Institute of Gastroenterology and Hepatology — Hanoi

Identifiers

NCT: NCT07127276 · AG2508

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗