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Not yet recruiting NCT07124533

Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

Phase III Interventional Gingival Inflammation Dental Caries

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Toothpaste Tablet, Conventional Toothpaste.
Who it may be relevant to
Registry conditions: Gingival Inflammation, Dental Caries. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences: A 6-week Randomized Controlled Trial

Overview

Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned dentifrice for 6 weeks. A pre and post-assessment measures the Gingival Index (GI) and Plaque Index (PI) and Decayed, Missing and Filled Teeth (DMFT). A questionnaire on the use of the product is distributed at the end of the study.

Interventions

  • Drug Toothpaste Tablet
    Denttabs toothpaste tablets
  • Drug Conventional Toothpaste
    Colgate Cavity Protection toothpaste

Primary outcome measures

  • Plaque Index Score at Baseline [Time frame: Change between baseline at visit 1 and visit 2, six weeks post baseline]
  • Gingival Index Score at Baseline [Time frame: Change between baseline at visit 1 and visit 2, six weeks post baseline]
Secondary outcome measures (2)
  • DMFT Score at Baseline [Time frame: Change between baseline at visit 1 and visit 2, six weeks post baseline]
  • Subject Perception of Product Use [Time frame: Visit 2 six weeks post study enrollment]

Eligibility criteria

Inclusion criteria

  • Subjects are 18 years or older;
  • Subjects who will comply with study protocol;
  • Subjects who can read and understand the consent form;
  • Subjects available during the study period;
  • Subjects have more than 20 teeth.

Exclusion criteria

1\. Subjects under the age of 18.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Prevention

Study locations

United States · 2 centers
  • Loma Linda University Health — Loma Linda
  • Loma Linda University — Loma Linda

Identifiers

NCT: NCT07124533 · 5250357

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗