Effect of Red and Blue Light Irradiation on Wound Healing After Hemorrhoid Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Red light exposure, Red-blue light exposure.
- Who it may be relevant to
- Registry conditions: Hemorrhoids. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Red and Blue Light Irradiation on Wound Healing After Hemorrhoid Surgery: A Single - Center Prospective Open - Label Randomized Clinical Trial
Overview
The subjects of this study were patients who took mixed haemorrhoidectomy during the period of December 2024 - December 2025 . The haemorrhoidectomy patients were randomly divided into routine group, red light group and red and blue light group, and were given different ways of trauma care, and the number of cases in each group was 105 , with a total of 305 cases. Observe the difference between red and blue light irradiation and routine care on the healing time of postoperative trauma and postoperative complications after haemorrhoidectomy, and evaluate the patients' quality of life and satisfaction with treatment under both red light irradiation and routine care.
Detailed description
The subjects of this study were patients who took mixed haemorrhoidectomy during the period of December 2024 - December 2025 . The diagnostic criteria were haemorrhoidal disease diagnosed as degree III-IV according to Goligher's classification. Inclusion criteria were 18 years \< age \< 75 years; diagnosis of haemorrhoids; internal haemorrhoid ligation + external haemorrhoidectomy. Exclusion criteria were patients with psychiatric disorders; patients with chronic diseases such as diabetes mellitus, hypertension and coronary artery disease; patients who underwent other treatments in addition to haemorrhoidectomy such as haemorrhoidal radiofrequency ablation/ sclerotherapy; patients who were unable to cooperate with the follow-up; and patients with perianal abscess, anal fissure, anal fistulae, and anorectal papillae hypertrophy. The haemorrhoidectomy patients were randomly divided into the conventional group, the red light group and the red and blue light group, and were given different ways of trauma care, and the number of cases in each group was 105 , with a total of 305 cases. The control group was given routine potassium permanganate sitz bath and routine care after internal haemorrhoid ligation + external haemorrhoidectomy to encourage patients to carry out functional exercise in moderation, mainly for anal lifting, buttock lifting and abdominal massage, etc.; the red light group was based on the control group, using red light irradiation for traumatic treatment; the red and blue light group was based on the control group, using red and blue light irradiation for traumatic treatment. Observe the difference between red and blue light irradiation and routine care on the healing time of postoperative trauma and postoperative complications after haemorrhoid surgery, and evaluate the patients' quality of life and satisfaction with treatment under both red light irradiation and routine care. Specific research content is to collect the postoperative data of the three groups of patients, including the recording of surgery-related pain scores, respectively, before the red light intervention and after the intervention of 1 d, 2 d, 3 d, 5 d, 7 d using visual analogue scoring (VAS) to assess the intensity of the patient's pain; the recording of the length of hospital stay; the recording of the degree of oedema of the anal verge were assessed before the red light intervention and after the intervention of 1 d, 2 d, 3 d, 5 d, 7 d, respectively, 0 Score 0: no oedema or slight oedema on the wound, but no impact on life. Score 2: oedema is present in only one area of the wound and is less than 1 cm in diameter, affecting daily activities. 4 points: multiple oedemas with a diameter of 1-2 cm, affecting daily activities. 6 points: multiple oedemas with a diameter of more than 2 cm, seriously affecting daily activities; follow up on the time to complete healing of the wound, quality of life scores, and the patient's satisfaction with the treatment.
Interventions
- Device Red light exposure
Patients in the red light group received red light therapy concurrently with standard care. - Device Red-blue light exposure
Patients in the red and blue light group received combined red and blue light therapy concurrently with standard care.
Primary outcome measures
- Wound healing time [Time frame: Daily from Day 1 until complete epithelialization (max 28 days post-op)]
Secondary outcome measures (4)
- Postoperative pain intensity (VAS score) [Time frame: Baseline, Day 1, 2, 3, 5, 7, and Day 14±2]
- Perianal edema severity (0-6 scale) [Time frame: Day 1, 2, 3, 5, 7, and Day 14±2]
- Length of hospital stay [Time frame: From surgery end to discharge (up to 7 days)]
- Complication incidence [Time frame: Within 30 days postoperatively]
Eligibility criteria
Inclusion criteria
- Aged 18-75 years
- Diagnosed with Grade III-IV hemorrhoids according to Goligher classification
- Scheduled to undergo rubber band ligation of internal hemorrhoids + external hemorrhoidectomy
- Willing and able to provide written informed consent
- Able to comply with postoperative follow-up and treatment protocol
Exclusion criteria
- Psychiatric disorders or cognitive impairment
- Uncontrolled chronic diseases:
- Diabetes (HbA1c >7.5%)
- Hypertension (BP >160/100 mmHg)
- Coronary artery disease (NYHA Class III-IV heart failure)
- Concurrent other hemorrhoid treatments (e.g., radiofrequency ablation/sclerotherapy)
- Inability to complete follow-up (e.g., living too far away, no stable contact)
- Concurrent anal disorders:
- Perianal abscess
- Anal fissure
- Anal fistula
- Hypertrophied anal papilla
- Pregnancy or lactation (for female patients)
- History of phototherapy allergy
- Participation in other clinical trials within 3 months
For registration, simply copy this structured list directly into the PRS system's eligibility section. The clear formatting will facilitate efficient review.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
China · 1 center
- Affiliated Hospital of Putian University — Putian
Identifiers
NCT: NCT07121686 · AHPutianU 2024212-1