The Role of Oxygen Reserve Index (ORi) in Apneic Ventilation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: OXYGEN RESERVE INDEX.
- Who it may be relevant to
- Registry conditions: Oxygen Reserve Index, Apnea, Ventilation, Body Mass Index. Basic parameters: 18 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Role of Oxygen Reserve Index (ORi) Monitoring in Optimizing Apneic Ventilation for Laparoscopic Cholecystectomy
Overview
Background: The Oxygen Reserve Index (ORI) is a non-invasive parameter utilizing multi-wavelength pulse co-oximetry. ORI can provide early warnings of deteriorating oxygenation before changes are reflected in SpO₂ levels. This study aimed to investigate the feasibility of non-ventilated intubation in patients undergoing cholecystectomy as a means to achieve safe intubation without nasogastric tube placement, with reduced trauma and cost, and improved time efficiency.
Detailed description
Obesity is a complex and chronic disease that significantly impacts respiratory physiology. It leads to increased work of breathing and reduced compliance of the chest wall. In morbidly obese individuals, there is a marked reduction in total lung capacity, vital capacity, forced expiratory volume in one second (FEV1), and forced vital capacity (FVC). Additionally, due to their elevated metabolic demands, these patients exhibit higher oxygen consumption rates.
The Oxygen Reserve Index (ORi) (Masimo Corp., Irvine, CA, USA) is an advanced, continuous, and non-invasive parameter that provides a relative indication of arterial partial pressure of oxygen (PaO₂).
ORI monitoring can be particularly beneficial in patients at risk for inadequate preoxygenation, those with difficult mask ventilation, hypoxemic patients with aspiration risk, rapid sequence induction scenarios, obese individuals, ICU intubations, and invasive ventilation cases. It has also been shown to provide early warnings of desaturation in select patient groups, contributing to improved patient safety.
Interventions
- Other OXYGEN RESERVE INDEX
Noted for each patient.
Primary outcome measures
- TIME FOR ORI TO FALL BELOW 0.24 [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
Secondary outcome measures (9)
- INITIAL ORI VALUE [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
- ORI VALUE AT 2 MINUTES [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
- AGE [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
- American Society of Anesthesiologists (ASA) Score [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
- SEX [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
- BMI [Time frame: WITHIN 10 MINUTES BEFORE INTUBATION]
- PRESENCE OF A NASOGASTRIC TUBE [Time frame: 10 MINUTES BEFORE EXTUBATION]
- Surgeon satisfaction [Time frame: 10 MINUTES BEFORE EXTUBATION]
- PRESENCE OF LARYNGOSPASM [Time frame: 10 MINUTES BEFORE EXTUBATION]
Eligibility criteria
Inclusion criteria
- 18-60 years
- ASA 1-2
- Mallampati score <2
- Scheduled for elective laparoscopic cholecystectomy under general anesthesia
Exclusion criteria
- <18 and >60 years
- ASA 3-4
- Initial ORI value below 0.24
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Turkey (Türkiye) · 1 center
- Ankara Bilkent City Hospital — Ankara
Identifiers
NCT: NCT07119866 · Oxygen Reserve Index